Literature DB >> 14526422

Distribution of variant genotypes of Fc gamma receptor IIIa in healthy Chinese population of Zhengzhou City.

Jun Wang1, Jianfei Feng, Li Zhang, Yu Hu, Bin Luan, Weihai Yue, Hong Wang, Shaoxian Zhu, Yumei Xu.   

Abstract

To investigate the distribution of variant genotypes of Fc gamma receptor IIIa (Fc gamma R IIIa) in healthy Chinese population of Zhengzhou city, genomic DNA was extracted from peripheral blood of healthy donators. The genotypes of Fc gamma R IIIa-158 were determined by nested polymerase chain reaction (PCR) in 137 healthy people in Zhengzhou city. The results showed that frequencies of variant genotypes FF, VV and VF were 42.3%, 48.9% and 8.8% respectively. The distribution of Fc gamma R IIIa-158 in healthy Chinese population of Zhengzhou city was polymorphic and different from that of African Americans (AA) and Caucasian Americans (CA).

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Year:  2003        PMID： 14526422     DOI： 10.1007/bf02829502

Source DB:  PubMed          Journal:  J Huazhong Univ Sci Technolog Med Sci        ISSN： 1672-0733


  8 in total

1.  Variant genotypes of the low-affinity Fcgamma receptors in two control populations and a review of low-affinity Fcgamma receptor polymorphisms in control and disease populations.

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Journal:  Blood       Date:  1999-12-15       Impact factor: 22.113

2.  A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.

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3.  The Fcgamma receptor IIIA-158F allele is a major risk factor for the development of lupus nephritis among Caucasians but not non-Caucasians.

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Journal:  Arthritis Rheum       Date:  2001-03

4.  Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype.

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Journal:  Blood       Date:  1997-08-01       Impact factor: 22.113

5.  Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups.

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Journal:  Arthritis Rheum       Date:  2000-10

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Journal:  Ann Hematol       Date:  1998-06       Impact factor: 3.673

7.  Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.

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Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

Review 8.  Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications.

Authors:  J G van de Winkel; P J Capel
Journal:  Immunol Today       Date:  1993-05
  8 in total
  1 in total

1.  Fc gamma receptor 3a genotype predicts overall survival in follicular lymphoma patients treated on SWOG trials with combined monoclonal antibody plus chemotherapy but not chemotherapy alone.

Authors:  Daniel O Persky; David Dornan; Bryan H Goldman; Rita M Braziel; Richard I Fisher; Michael Leblanc; David G Maloney; Oliver W Press; Thomas P Miller; Lisa M Rimsza
Journal:  Haematologica       Date:  2012-01-22       Impact factor: 9.941
  1 in total

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