Literature DB >> 1452615

High-performance liquid chromatographic determination of ambroxol in human plasma.

M Nobilis1, J Pastera, D Svoboda, J Kvêtina, K Macek.   

Abstract

Ambroxol has been determined in biological fluids using a rapid and sensitive high-performance liquid chromatographic method. The samples prepared from plasma by liquid-liquid extraction were analysed on reversed-phase silica gel by competing-ion chromatography with ultraviolet detection. The method was applied to the determination of ambroxol levels in twelve healthy volunteers after oral administration of 90 mg of ambroxol in tablets of Mucosolvan and Ambrosan.

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Year:  1992        PMID: 1452615     DOI: 10.1016/0378-4347(92)80278-x

Source DB:  PubMed          Journal:  J Chromatogr


  2 in total

1.  Ambroxol lozenge bioavailability : an open-label, two-way crossover study of the comparative bioavailability of ambroxol lozenges and commercial tablets in healthy thai volunteers.

Authors:  Malee Rojpibulstit; Srirat Kasiwong; Siwasak Juthong; Narubodee Phadoongsombat; Damrongsak Faroongsarng
Journal:  Clin Drug Investig       Date:  2003       Impact factor: 2.859

2.  Simultaneous UV Spectrophotometric Estimation of Ambroxol Hydrochloride and Levocetirizine Dihydrochloride.

Authors:  S Lakshmana Prabhu; A A Shirwaikar; Annie Shirwaikar; C Dinesh Kumar; G Aravind Kumar
Journal:  Indian J Pharm Sci       Date:  2008 Mar-Apr       Impact factor: 0.975

  2 in total

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