David L Knox1, Terrence P O'Brien, W Richard Green. 1. Eye Pathology Laboratory, Wilmer Institute and Department of Pathology, Johns Hopkins Medical Institution, 600 North Wolfe Street, Baltimore, MD 21287-9248, USA.
Abstract
PURPOSE: To describe the clinical and pathologic features of a conjunctival granuloma resulting from Histoplasma capsulatum. DESIGN: Clinicopathologic case report. METHODS: Surgical excision of conjunctival lesion, histopathologic study with special stains, and a fluorescent antibody technique. RESULTS: A conjunctiva granuloma was found to contain microorganisms, compatible with H. capsulatum, confirmed by a fluorescent antibody technique. The conjunctiva returned to normal. CONCLUSIONS: A focal granuloma of the conjunctiva contained H. capsulatum in a patient whose recent symptoms suggested primary infection. The conjunctival lesion was similar to mucocutaneous lesions seen in patients with systemic histoplasmosis.
PURPOSE: To describe the clinical and pathologic features of a conjunctival granuloma resulting from Histoplasma capsulatum. DESIGN: Clinicopathologic case report. METHODS: Surgical excision of conjunctival lesion, histopathologic study with special stains, and a fluorescent antibody technique. RESULTS: A conjunctiva granuloma was found to contain microorganisms, compatible with H. capsulatum, confirmed by a fluorescent antibody technique. The conjunctiva returned to normal. CONCLUSIONS: A focal granuloma of the conjunctiva contained H. capsulatum in a patient whose recent symptoms suggested primary infection. The conjunctival lesion was similar to mucocutaneous lesions seen in patients with systemic histoplasmosis.