Literature DB >> 14522251

Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics.

Kun Ping Lu1.   

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Year:  2003        PMID： 14522251     DOI： 10.1016/s1535-6108(03)00218-6

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


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  48 in total

1.  Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage.

Authors:  Michael Berger; Nathalie Stahl; Giannino Del Sal; Ygal Haupt
Journal:  Mol Cell Biol       Date:  2005-07       Impact factor: 4.272

2.  Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function.

Authors:  Tae Ho Lee; Chun-Hau Chen; Futoshi Suizu; Pengyu Huang; Cordelia Schiene-Fischer; Sebastian Daum; Yan Jessie Zhang; Alison Goate; Ruey-Hwa Chen; Xiao Zhen Zhou; Kun Ping Lu
Journal:  Mol Cell       Date:  2011-04-14       Impact factor: 17.970

3.  Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer.

Authors:  Qingqing Ding; Longfei Huo; Jer-Yen Yang; Weiya Xia; Yongkun Wei; Yong Liao; Chun-Ju Chang; Yan Yang; Chien-Chen Lai; Dung-Fang Lee; Chia-Jui Yen; Yun-Ju Rita Chen; Jung-Mao Hsu; Hsu-Ping Kuo; Chun-Yi Lin; Fuu-Jen Tsai; Long-Yuan Li; Chang-Hai Tsai; Mien-Chie Hung
Journal:  Cancer Res       Date:  2008-08-01       Impact factor: 12.701

4.  Pin1 deficiency causes endothelial dysfunction and hypertension.

Authors:  Valorie L Chiasson; Nidhi Munshi; Piyali Chatterjee; Kristina J Young; Brett M Mitchell
Journal:  Hypertension       Date:  2011-08-01       Impact factor: 10.190

5.  FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-κB signaling.

Authors:  J Wang; P S Ray; M-S Sim; X Z Zhou; K P Lu; A V Lee; X Lin; S P Bagaria; A E Giuliano; X Cui
Journal:  Oncogene       Date:  2012-01-16       Impact factor: 9.867

6.  Synthetic lethality of retinoblastoma mutant cells in the Drosophila eye by mutation of a novel peptidyl prolyl isomerase gene.

Authors:  Kyle A Edgar; Marcia Belvin; Annette L Parks; Kellie Whittaker; Matt B Mahoney; Monique Nicoll; Christopher C Park; Christopher G Winter; Feng Chen; Kim Lickteig; Ferhad Ahmad; Hanife Esengil; Matthew V Lorenzi; Amanda Norton; Brent A Rupnow; Laleh Shayesteh; Mariano Tabios; Lynn M Young; Pamela M Carroll; Casey Kopczynski; Gregory D Plowman; Lori S Friedman; Helen L Francis-Lang
Journal:  Genetics       Date:  2005-03-02       Impact factor: 4.562

7.  Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis.

Authors:  Gerburg Wulf; Priti Garg; Yih-Cherng Liou; Dirk Iglehart; Kun Ping Lu
Journal:  EMBO J       Date:  2004-07-15       Impact factor: 11.598

8.  The prolyl isomerase Pin1 is overexpressed in human esophageal cancer.

Authors:  Huawei Jin; Jie Jiang; Lifang Sun; Fangfang Zheng; Chengyan Wu; Lin Peng; Yufen Zhao; Xueji Wu
Journal:  Oncol Lett       Date:  2011-08-23       Impact factor: 2.967

9.  Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.

Authors:  Amy S Farrell; Carl Pelz; Xiaoyan Wang; Colin J Daniel; Zhiping Wang; Yulong Su; Mahnaz Janghorban; Xiaoli Zhang; Charlie Morgan; Soren Impey; Rosalie C Sears
Journal:  Mol Cell Biol       Date:  2013-05-28       Impact factor: 4.272

10.  A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity.

Authors:  Jiachun Lu; Zhibin Hu; Sheng Wei; Li-E Wang; Zhensheng Liu; Adel K El-Naggar; Erich M Sturgis; Qingyi Wei
Journal:  Carcinogenesis       Date:  2009-07-22       Impact factor: 4.944
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