Literature DB >> 14522143

New roles for astrocytes (stars at last).

Bruce Ransom1, Toby Behar, Maiken Nedergaard.   

Abstract

Astrocytes have been presumed to be uninteresting for the better part of a century. Recent findings suggest unexpected new functions for these cells and highlight the importance of viewing most brain activities as a collaboration between astrocytes and neurons. Astrocytes have been implicated in dynamic regulation of neuron production, synaptic network formation, neuron electrical activity and specific neurological diseases. We are only at the threshold of understanding fully the nature and consequences of these new astrocyte functions, and there is still much to be learned about the older and better-known roles. But now, at last, astrocytes have our attention.

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Year:  2003        PMID: 14522143     DOI: 10.1016/j.tins.2003.08.006

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN: 0166-2236            Impact factor:   13.837


  92 in total

1.  Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines.

Authors:  Cécile Mahé; Michel Bernhard; Ionel Bobirnac; Corinna Keser; Erika Loetscher; Dominik Feuerbach; Kumlesh K Dev; Philippe Schoeffter
Journal:  Br J Pharmacol       Date:  2004-08-31       Impact factor: 8.739

2.  Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

Authors:  Lijun Xu; John F Emery; Yi-Bing Ouyang; Ludmila A Voloboueva; Rona G Giffard
Journal:  Glia       Date:  2010-07       Impact factor: 7.452

3.  An astrocytic basis of epilepsy.

Authors:  Guo-Feng Tian; Hooman Azmi; Takahiro Takano; Qiwu Xu; Weiguo Peng; Jane Lin; NancyAnn Oberheim; Nanhong Lou; Xiaohai Wang; H Ronald Zielke; Jian Kang; Maiken Nedergaard
Journal:  Nat Med       Date:  2005-08-14       Impact factor: 53.440

4.  The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways.

Authors:  Yongmei Zhao; Mark A Rivieccio; Sarah Lutz; Eliana Scemes; Celia F Brosnan
Journal:  Glia       Date:  2006-12       Impact factor: 7.452

Review 5.  Targeted activation of astrocytes: a potential neuroprotective strategy.

Authors:  Carole Escartin; Gilles Bonvento
Journal:  Mol Neurobiol       Date:  2008-10-18       Impact factor: 5.590

6.  Vasodilation by in vivo activation of astrocyte endfeet via two-photon calcium uncaging as a strategy to prevent brain ischemia.

Authors:  Yuanxin Chen; James Mancuso; Zhen Zhao; Xuping Li; Jie Cheng; Gustavo Roman; Stephen T C Wong
Journal:  J Biomed Opt       Date:  2013-12       Impact factor: 3.170

7.  Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes.

Authors:  Jyoti K Jaiswal; Marina Fix; Takahiro Takano; Maiken Nedergaard; Sanford M Simon
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-21       Impact factor: 11.205

8.  Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.

Authors:  Vikas V Dukhande; Ivana Kawikova; Alfred L M Bothwell; James C K Lai
Journal:  Apoptosis       Date:  2013-06       Impact factor: 4.677

Review 9.  What is the role of astrocyte calcium in neurophysiology?

Authors:  Cendra Agulhon; Jeremy Petravicz; Allison B McMullen; Elizabeth J Sweger; Suzanne K Minton; Sarah R Taves; Kristen B Casper; Todd A Fiacco; Ken D McCarthy
Journal:  Neuron       Date:  2008-09-25       Impact factor: 17.173

10.  Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin.

Authors:  Jennifer V Welser-Alves; Richard Milner
Journal:  Neurochem Int       Date:  2013-04-22       Impact factor: 3.921

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