Literature DB >> 14521562

Leg ulcer in hereditary spherocytosis.

Susana Giraldi1, Kerstin T Abbage, Leide P Marinoni, Vania Oliveira, Mara A Pianowski, Adelina E Lehmkuhl, José Fillus Neto.   

Abstract

Indolent leg ulcers are a rare complication found in patients with hereditary spherocytosis. We report a 13-year-old girl with hereditary spherocytosis who developed a chronic painful ulcer on the medial malleolus. All other etiologies were ruled out. Nine months after splenectomy the ulcer healed completely and the symptoms disappeared. We discuss and review this unusual entity in children.

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Year:  2003        PMID： 14521562     DOI： 10.1046/j.1525-1470.2003.20512.x

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN： 0736-8046            Impact factor:   1.588


  8 in total

1.  Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease.

Authors:  Gregory J Kato; Vicki McGowan; Roberto F Machado; Jane A Little; James Taylor; Claudia R Morris; James S Nichols; Xunde Wang; Mirjana Poljakovic; Sidney M Morris; Mark T Gladwin
Journal:  Blood       Date:  2005-11-15       Impact factor: 22.113

2.  Whole-exome sequencing indicates FLG2 variant associated with leg ulcers in Brazilian sickle cell anemia patients.

Authors:  Gabriela Queila de Carvalho-Siqueira; Galina Ananina; Bruno Batista de Souza; Murilo Guimarães Borges; Mirta Tomie Ito; Sueli Matilde da Silva-Costa; Igor de Farias Domingos; Diego Arruda Falcão; Iscia Lopes-Cendes; Marcos André Cavalcanti Bezerra; Aderson da Silva Araújo; Antônio Roberto Lucena-Araújo; Marilda de Souza Gonçalves; Sara Teresinha Olalla Saad; Fernando Ferreira Costa; Mônica Barbosa de Melo
Journal:  Exp Biol Med (Maywood)       Date:  2019-05-12

3.  Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway.

Authors:  Vikki G Nolan; Adeboye Adewoye; Clinton Baldwin; Ling Wang; Qianli Ma; Diego F Wyszynski; John J Farrell; Paola Sebastiani; Lindsay A Farrer; Martin H Steinberg
Journal:  Br J Haematol       Date:  2006-06       Impact factor: 6.998

Review 4.  Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes.

Authors:  Gregory J Kato; Mark T Gladwin; Martin H Steinberg
Journal:  Blood Rev       Date:  2006-11-07       Impact factor: 8.250

5.  Lupus anticoagulant and leg ulcers in sickle cell anemia.

Authors:  Edeghonghon E Olayemi; Godwin N Bazuaye
Journal:  Indian J Dermatol       Date:  2009-07       Impact factor: 1.494

6.  Vasculopathy, inflammation, and blood flow in leg ulcers of patients with sickle cell anemia.

Authors:  Caterina P Minniti; Kara-Marie H Delaney; Alexander M Gorbach; Dihua Xu; Chyi-Chia Richard Lee; Nitin Malik; Antony Koroulakis; Matthew Antalek; Jordan Maivelett; Marlene Peters-Lawrence; Enrico M Novelli; Sophie M Lanzkron; Karen C Axelrod; Gregory J Kato
Journal:  Am J Hematol       Date:  2013-09-19       Impact factor: 10.047

7.  Leg ulcers in sickle cell disease: current patterns and practices.

Authors:  Kara-Marie H Delaney; Karen C Axelrod; Ashley Buscetta; Kathryn L Hassell; Patricia E Adams-Graves; Catherine Seamon; Gregory J Kato; Caterina P Minniti
Journal:  Hemoglobin       Date:  2013-04-19       Impact factor: 0.849

8.  Decreased hematocrit-to-viscosity ratio and increased lactate dehydrogenase level in patients with sickle cell anemia and recurrent leg ulcers.

Authors:  Philippe Connes; Yann Lamarre; Marie-Dominique Hardy-Dessources; Nathalie Lemonne; Xavier Waltz; Danièle Mougenel; Martin Mukisi-Mukaza; Marie-Laure Lalanne-Mistrih; Vanessa Tarer; Benoit Tressières; Maryse Etienne-Julan; Marc Romana
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240
  8 in total

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