Literature DB >> 14520672

Retinal involvement in dementia with Lewy bodies: a clue to hallucinations?

Claude-Alain Maurage1, Marie-Magdeleine Ruchoux, Rob de Vos, Andrei Surguchov, Alain Destee.   

Abstract

Visual hallucinations are a core feature of dementia with Lewy bodies. Their pathophysiology is not well understood, because neither clinical nor histological data have shown their basic mechanisms. Here, we report the presence of pale inclusions in the outer plexiform layer of the retina in a patient with dementia with Lewy bodies. These inclusions are related to cytoskeletal disorganization of the cones at ultrastructural level and modifications of the immunohistochemical pattern of distribution of synucleins in the retina. These modifications may participate in the visual impairment in dementia with Lewy bodies.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14520672     DOI： 10.1002/ana.10730

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  17 in total

Review 1.  Visual spatial cognition in neurodegenerative disease.

Authors:  Katherine L Possin
Journal:  Neurocase       Date:  2010-06-02       Impact factor: 0.881

2.  Phosphorylated α-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects.

Authors:  Thomas G Beach; Jeremiah Carew; Geidy Serrano; Charles H Adler; Holly A Shill; Lucia I Sue; Marwan N Sabbagh; Haruhiko Akiyama; Nicolás Cuenca
Journal:  Neurosci Lett       Date:  2014-04-28       Impact factor: 3.046

Review 3.  Pathophysiology and treatment of psychosis in Parkinson's disease: a review.

Authors:  Laura B Zahodne; Hubert H Fernandez
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

4.  Beta-amyloid, phospho-tau and alpha-synuclein deposits similar to those in the brain are not identified in the eyes of Alzheimer's and Parkinson's disease patients.

Authors:  Cheng-Ying Ho; Juan C Troncoso; David Knox; Walter Stark; Charles G Eberhart
Journal:  Brain Pathol       Date:  2013-06-28       Impact factor: 6.508

Review 5.  Hallucinations in Parkinson disease.

Authors:  Nico J Diederich; Gilles Fénelon; Glenn Stebbins; Christopher G Goetz
Journal:  Nat Rev Neurol       Date:  2009-06       Impact factor: 42.937

Review 6.  Visuo-cognitive skill deficits in Alzheimer's disease and Lewy body disease: A comparative analysis.

Authors:  Xuemei Li; Priyanka Rastogi; Jeffrey A Gibbons; Suprakash Chaudhury
Journal:  Ann Indian Acad Neurol       Date:  2014-01       Impact factor: 1.383

7.  Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations.

Authors:  Ahmad A Khundakar; Peter S Hanson; Daniel Erskine; Nichola Z Lax; Joseph Roscamp; Evangelia Karyka; Eliona Tsefou; Preeti Singh; Simon J Cockell; Andrew Gribben; Lynne Ramsay; Peter G Blain; Urs P Mosimann; Deborah J Lett; Matthias Elstner; Douglass M Turnbull; Charles C Xiang; Michael J Brownstein; John T O'Brien; John-Paul Taylor; Johannes Attems; Alan J Thomas; Ian G McKeith; Christopher M Morris
Journal:  Acta Neuropathol Commun       Date:  2016-06-30       Impact factor: 7.801

8.  Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.

Authors:  Christian Schön; Nadine A Hoffmann; Simon M Ochs; Steffen Burgold; Severin Filser; Sonja Steinbach; Mathias W Seeliger; Thomas Arzberger; Michel Goedert; Hans A Kretzschmar; Boris Schmidt; Jochen Herms
Journal:  PLoS One       Date:  2012-12-31       Impact factor: 3.240

9.  Effect of optical flow versus attentional strategy on gait in Parkinson's Disease: a study with a portable optical stimulating device.

Authors:  Maurizio Ferrarin; Marco Rabuffetti; Mauro Tettamanti; Riccardo Pignatti; Alessandro Mauro; Giovanni Albani
Journal:  J Neuroeng Rehabil       Date:  2008-01-18       Impact factor: 4.262

10.  γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway.

Authors:  Corina Wilding; Katharina Bell; Sabine Beck; Sebastian Funke; Norbert Pfeiffer; Franz H Grus
Journal:  PLoS One       Date:  2014-03-03       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.