BACKGROUND: Understanding of the impact of depressive and anxiety disorders on functional health status in the context of chronic medical illness has been gained almost exclusively from the study of patient populations. AIMS: To compare the impact of major depressive and generalised anxiety disorder with that of chronic medical conditions on functional health in a UK resident population. METHOD: The functional health of 20,921 study participants was assessed using the Medical Outcomes Study Short Form 36 questionnaire. Depressive and anxiety disorder episode histories and chronic medical conditions were assessed using independent self-completed questionnaires. RESULTS: The degree of physical functional impairment associated with mood disorders was of equivalent magnitude to that associated with the presence of chronic medical conditions or with being some 12 years older. CONCLUSIONS: Depressive and anxiety disorders have a profound impact on functional health that is independent of chronic medical illness. Chronic anxiety is associated with physical health limitations in excess of those associated with chronic depression or any of the physical health conditions considered, except for stroke.
BACKGROUND: Understanding of the impact of depressive and anxiety disorders on functional health status in the context of chronic medical illness has been gained almost exclusively from the study of patient populations. AIMS: To compare the impact of major depressive and generalised anxiety disorder with that of chronic medical conditions on functional health in a UK resident population. METHOD: The functional health of 20,921 study participants was assessed using the Medical Outcomes Study Short Form 36 questionnaire. Depressive and anxiety disorder episode histories and chronic medical conditions were assessed using independent self-completed questionnaires. RESULTS: The degree of physical functional impairment associated with mood disorders was of equivalent magnitude to that associated with the presence of chronic medical conditions or with being some 12 years older. CONCLUSIONS: Depressive and anxiety disorders have a profound impact on functional health that is independent of chronic medical illness. Chronic anxiety is associated with physical health limitations in excess of those associated with chronic depression or any of the physical health conditions considered, except for stroke.
Authors: I Reinders; R A Murphy; X Song; M Visser; M F Cotch; T F Lang; M E Garcia; L J Launer; K Siggeirsdottir; G Eiriksdottir; P V Jonsson; V Gudnason; T B Harris; I A Brouwer Journal: Eur J Clin Nutr Date: 2015-01-14 Impact factor: 4.016
Authors: Kelechi E Nnoaham; Lone Hummelshoj; Premila Webster; Thomas d'Hooghe; Fiorenzo de Cicco Nardone; Carlo de Cicco Nardone; Crispin Jenkinson; Stephen H Kennedy; Krina T Zondervan Journal: Fertil Steril Date: 2011-06-30 Impact factor: 7.329
Authors: David Melzer; Timothy M Frayling; Anna Murray; Alison J Hurst; Lorna W Harries; Honglin Song; Kaytee Khaw; Robert Luben; Paul G Surtees; Stefania S Bandinelli; Anna-Maria Corsi; Luigi Ferrucci; Jack M Guralnik; Robert B Wallace; Andrew T Hattersley; Paul D Pharoah Journal: Mech Ageing Dev Date: 2007-03-27 Impact factor: 5.432
Authors: Nicholas W J Wainwright; Paul G Surtees; Ailsa A Welch; Robert N Luben; Kay-Tee Khaw; Sheila A Bingham Journal: J Epidemiol Community Health Date: 2007-10 Impact factor: 3.710