| Literature DB >> 14519392 |
Kris A DeMali1, Krister Wennerberg, Keith Burridge.
Abstract
Integrin engagement stimulates the activity of numerous signaling molecules, including the Rho family of GTPases, tyrosine phosphatases, cAMP-dependent protein kinase and protein kinase C, and stimulates production of PtdIns(4,5)P2. Integrins promote actin assembly via the recruitment of molecules that directly activate the actin polymerization machinery or physically link it to sites of cell adhesion.Entities:
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Year: 2003 PMID: 14519392 DOI: 10.1016/s0955-0674(03)00109-1
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382