Literature DB >> 145190

Thymoxamine and intraocular pressure.

L Bonomi, L Tomazzoli.   

Abstract

Topical treatment with 1% thymoxamine produces in rabbit and human eyes a small but real miotic and tension-lowering effect. The latter is more evident using two different models of experimental ocular hypertension in rabbits. In human open-angle glaucoma eyes, tonographic measurements indicate that the outflow facility is left unchanged by the drug.

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Year:  1977        PMID: 145190     DOI: 10.1007/bf00414710

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN: 0065-6100


  7 in total

1.  [Sympatholytic effect on the eye of local conjunctival application of opilon].

Authors:  H PAU
Journal:  Klin Monbl Augenheilkd Augenarztl Fortbild       Date:  1955

2.  An improved model of experimentally induced ocular hypertension in the rabbit.

Authors:  L Bonomi; L Tomazzoli; D Jaria
Journal:  Invest Ophthalmol       Date:  1976-09

3.  Safe mydriasis.

Authors:  R Mapstone
Journal:  Br J Ophthalmol       Date:  1970-10       Impact factor: 4.638

4.  Drug therapy of glaucoma.

Authors:  G D Paterson; G Paterson
Journal:  Br J Ophthalmol       Date:  1972-03       Impact factor: 4.638

5.  Alpha-adrenergic receptor blockade in the treatment of angle-closure glaucoma.

Authors:  P C Rutkowski; J L Fernández; M A Galin; A H Halasa
Journal:  Trans Am Acad Ophthalmol Otolaryngol       Date:  1973 Mar-Apr

6.  Alpha receptor blockade by thymoxamine in the human eye.

Authors:  P Turner; J M Sneddon
Journal:  Clin Pharmacol Ther       Date:  1968 Jan-Feb       Impact factor: 6.875

7.  Thymoxamine hydrochloride: effects on the facility of outflow and intraocular pressure.

Authors:  M Wand; W M Grant
Journal:  Invest Ophthalmol       Date:  1976-05
  7 in total
  3 in total

1.  Ocular hypotensive action of labetalol in rabbit and human eyes.

Authors:  L Bonomi; S Perfetti; R Bellucci; F Massa; E Noya
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1981

2.  Thymoxamine: a miotic for intraocular use.

Authors:  F Grehn; T Fleig; E Schwarzmüller
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1986       Impact factor: 3.117

3.  Pharmacokinetics of thymoxamine in rabbits after ophthalmic and intravenous administration.

Authors:  I Aldana; E González-Peñas; D Fos; L Bruseghini; A Esteras; N Ceppi Monti; V Gianesello
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1994 Apr-Jun       Impact factor: 2.441

  3 in total

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