Literature DB >> 14518992

A stereodivergent approach to chiral nonracemic N-protected alpha,alpha-dialkylated amino acids.

Claude Spino1, Cédrickx Godbout, Cédrickx Gobdout.   

Abstract

Menthyl carboxaldehyde is used as a chiral auxiliary to make quaternary amino acids of either configuration via a stereodivergent approach that includes an SN2' displacement by a cuprate reagent and a Curtius rearrangement as key steps.

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Year:  2003        PMID: 14518992     DOI: 10.1021/ja037078a

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  2 in total

1.  Total synthesis of herboxidiene/GEX 1A.

Authors:  Yun Zhang; James S Panek
Journal:  Org Lett       Date:  2007-07-13       Impact factor: 6.005

Review 2.  Toward ideal carbon dioxide functionalization.

Authors:  Yang Yang; Ji-Woong Lee
Journal:  Chem Sci       Date:  2019-02-20       Impact factor: 9.825

  2 in total

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