Literature DB >> 14518919

Relationship between rate and distance.

Fredric M Menger1, Ashley L Galloway, Djamaladdin G Musaev.   

Abstract

The activation energies for four Smiles reactions vary with the distance squared between the nucleophilic and electrophilic atoms (consistent with theoretical considerations and pertinent to organic and enzymatic catalyses).

Year:  2003        PMID： 14518919     DOI： 10.1039/b306342a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Design, synthesis and in vitro kinetic study of tranexamic acid prodrugs for the treatment of bleeding conditions.

Authors:  Rafik Karaman; Hiba Ghareeb; Khuloud Kamal Dajani; Laura Scrano; Hussein Hallak; Saleh Abu-Lafi; Gennaro Mecca; Sabino A Bufo
Journal:  J Comput Aided Mol Des       Date:  2013-07-24       Impact factor: 3.686

2.  Computationally designed prodrugs of statins based on Kirby's enzyme model.

Authors:  Rafik Karaman; Wajd Amly; Laura Scrano; Gennaro Mecca; Sabino A Bufo
Journal:  J Mol Model       Date:  2013-07-09       Impact factor: 1.810

3.  Computer-assisted design for paracetamol masking bitter taste prodrugs.

Authors:  Hatem Hejaz; Rafik Karaman; Mustafa Khamis
Journal:  J Mol Model       Date:  2011-04-15       Impact factor: 1.810

4.  Computer-assisted design for atenolol prodrugs for the use in aqueous formulations.

Authors:  Rafik Karaman; Khuloud Dajani; Hussein Hallak
Journal:  J Mol Model       Date:  2011-07-23       Impact factor: 1.810

5.  Prodrugs of aza nucleosides based on proton transfer reaction.

Authors:  Rafik Karaman
Journal:  J Comput Aided Mol Des       Date:  2010-10-13       Impact factor: 3.686

Review 6.  Enzyme Models-From Catalysis to Prodrugs.

Authors:  Zeinab Breijyeh; Rafik Karaman
Journal:  Molecules       Date:  2021-05-28       Impact factor: 4.411

7.  Design, synthesis, and in vitro kinetics study of atenolol prodrugs for the use in aqueous formulations.

Authors:  Rafik Karaman; Alaa Qtait; Khulod Khayyat Dajani; Saleh Abu Lafi
Journal:  ScientificWorldJournal       Date:  2014-01-12
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.