Literature DB >> 14518514

Electrical treatment of coma via the median nerve.

E B Cooper1, J B Cooper.   

Abstract

The median nerve is a portal to interact with the injured comatose brain. Peripheral nerve electrical stimulation has a central nervous system effect. Two to three weeks of right median nerve stimulation (RMNS) can hasten awakening from deep coma by increasing the dopamine levels. Three cases of electrically treated GCS-4 teenagers with acute diffuse brain injuries from motor vehicle crashes are presented by video. Pilot studies of RMNS for acute post-traumatic coma states have been done over the last ten years at East Carolina University and the University of Virginia. The neurophysiological effects of RMNS have been well documented at several neurosurgical centers in Japan using neuroimaging and spinal fluid assays. RMNS is a safe, inexpensive, non-invasive therapy for neuro-resuscitation of coma patients. When employed early in the coma, the time in the ICU may be shortened and the quality of the final outcome may be enhanced.

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Mesh:

Year:  2003        PMID: 14518514     DOI: 10.1007/978-3-7091-6081-7_2

Source DB:  PubMed          Journal:  Acta Neurochir Suppl        ISSN: 0065-1419


  5 in total

1.  MicroRNA alteration in cerebrospinal fluid from comatose patients with traumatic brain injury after right median nerve stimulation.

Authors:  Ying Jia; Yi-Fan He; Ye Tian; Yuan-Zhi Wang; Rui-Ting Zhao; Xiao-Chun Li; Jian Sun; Ying-Sheng Wei; Shuo An; Heng-Jie Yuan; Chun-Xiao Wan; Rong-Cai Jiang
Journal:  Exp Brain Res       Date:  2022-08-07       Impact factor: 2.064

2.  A Narrative Review of Pharmacologic and Non-pharmacologic Interventions for Disorders of Consciousness Following Brain Injury in the Pediatric Population.

Authors:  Nathan K Evanson; Andrea L Paulson; Brad G Kurowski
Journal:  Curr Phys Med Rehabil Rep       Date:  2016-02-17

3.  Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation.

Authors:  Zhen Feng; Qing Du
Journal:  Neural Regen Res       Date:  2016-06       Impact factor: 5.135

4.  Right median nerve electrical stimulation for acute traumatic coma (the Asia Coma Electrical Stimulation trial): study protocol for a randomised controlled trial.

Authors:  Xiang Wu; Chao Zhang; Junfeng Feng; Qing Mao; Guoyi Gao; Jiyao Jiang
Journal:  Trials       Date:  2017-07-10       Impact factor: 2.279

5.  Virtual Reality-Based Sensory Stimulation for Pediatric Disorders of Consciousness: A Pilot Study.

Authors:  Piao Liang; Hong Xu; Sinan Li; Lei Ren; Xiaoke Zhao
Journal:  Front Pediatr       Date:  2022-06-13       Impact factor: 3.569

  5 in total

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