Literature DB >> 14517601

[Minimally invasive therapy of painful osteoporotic vertebral fractures].

P Krepler1, J G Grohs.   

Abstract

INTRODUCTION: Osteoporosis is the most common bone disease. Due to an increase of the older population an higher impact of osteoporosis and its treatment can be expected.
BACKGROUND: Painful osteoporotic vertebral fractures result in an increased morbidity and mortality. Standard treatment of painful osteoporotic vertebral fractures comprises analgetics, bed rest and, if needed, orthotics.
METHOD: By mere augmentation of the vertebra with polymethylmet acrylate (PMMA), the so called "vertebroplasty" a good pain reduction and increase in function and quality of life can be achieved. With the technique of kyphoplasty (Kyphon) it is feasible to correct a kyphotic deformity. Inflatable balloons are introduced to the vertebra to lift the endplates. The created cavity is filled with bone cement (PMMA). DISCUSSION: Kyphoplasty is able to correct osteoporosis induced kyphotic deformity. Compared to the technique of vertebroplasty, kyphoplasty is less risky but is more time consuming and more expensive. Time will show whether the expected advantage of deformity correction will result in a better outcome for the patient, e. g. in a lower incidence of refractures.

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Year:  2003        PMID: 14517601     DOI: 10.1007/s00117-003-0949-9

Source DB:  PubMed          Journal:  Radiologe        ISSN: 0033-832X            Impact factor:   0.635


  9 in total

1.  Vertebral fractures.

Authors:  C Cooper; L J Melton
Journal:  BMJ       Date:  1992-03-28

2.  Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results.

Authors:  H Deramond; C Depriester; P Galibert; D Le Gars
Journal:  Radiol Clin North Am       Date:  1998-05       Impact factor: 2.303

3.  Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty.

Authors:  B Padovani; O Kasriel; P Brunner; P Peretti-Viton
Journal:  AJNR Am J Neuroradiol       Date:  1999-03       Impact factor: 3.825

4.  Initial outcome and efficacy of "kyphoplasty" in the treatment of painful osteoporotic vertebral compression fractures.

Authors:  I H Lieberman; S Dudeney; M K Reinhardt; G Bell
Journal:  Spine (Phila Pa 1976)       Date:  2001-07-15       Impact factor: 3.468

5.  Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study.

Authors:  B Cortet; A Cotten; N Boutry; R M Flipo; B Duquesnoy; P Chastanet; B Delcambre
Journal:  J Rheumatol       Date:  1999-10       Impact factor: 4.666

6.  The clinical consequences of vertebral compression fracture.

Authors:  S L Silverman
Journal:  Bone       Date:  1992       Impact factor: 4.398

7.  Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group.

Authors:  D M Kado; W S Browner; L Palermo; M C Nevitt; H K Genant; S R Cummings
Journal:  Arch Intern Med       Date:  1999-06-14

8.  [Percutaneous injection of methyl-metacrylate in osteoporosis and severe vertebral osteolysis (Galibert's technic)].

Authors:  C Lapras; C Mottolese; R Deruty; C Lapras; J Remond; J Duquesnel
Journal:  Ann Chir       Date:  1989

Review 9.  Perspective. How many women have osteoporosis?

Authors:  L J Melton; E A Chrischilles; C Cooper; A W Lane; B L Riggs
Journal:  J Bone Miner Res       Date:  1992-09       Impact factor: 6.741

  9 in total

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