Literature DB >> 14513359

No evidence for DUP25 in patients with panic disorder using a quantitative real-time PCR approach.

Johannes Schumacher1, Andreas C J Otte, Tim Becker, Yuli Sun, Thomas F Wienker, Brunhilde Wirth, Petra Franke, Rami Abou Jamra, Peter Propping, Jürgen Deckert, Markus M Nöthen, Sven Cichon.   

Abstract

A duplication of chromosome 15q24-q26 (DUP25) has been reported to be associated with anxiety disorders. We tested for the presence of DUP25 in a sample of 50 patients with panic disorder and 50 controls using a quantitative real-time PCR approach. Contrary to the original finding, our results were compatible with the absence of DUP25, and no significant difference could be detected between patients and controls ( P=1.0). Thus, our study does not support the hypothesis of an involvement of DUP25 in panic disorder.

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Year:  2003        PMID： 14513359     DOI： 10.1007/s00439-003-1022-5

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  7 in total

1.  A multicolor FISH assay does not detect DUP25 in control individuals or in reported positive control cells.

Authors:  Yanina Weiland; Jürgen Kraus; Michael R Speicher
Journal:  Am J Hum Genet       Date:  2003-05       Impact factor: 11.025

2.  Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy.

Authors:  Markus Feldkötter; Verena Schwarzer; Radu Wirth; Thomas F Wienker; Brunhilde Wirth
Journal:  Am J Hum Genet       Date:  2001-12-21       Impact factor: 11.025

3.  A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders.

Authors:  M Gratacòs; M Nadal; R Martín-Santos; M A Pujana; J Gago; B Peral; L Armengol; I Ponsa; R Miró; A Bulbena; X Estivill
Journal:  Cell       Date:  2001-08-10       Impact factor: 41.582

4.  The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures.

Authors:  L N Robins; J Wing; H U Wittchen; J E Helzer; T F Babor; J Burke; A Farmer; A Jablenski; R Pickens; D A Regier
Journal:  Arch Gen Psychiatry       Date:  1988-12

5.  Neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) and panic disorder: an association study.

Authors:  O K Steinlein; J Deckert; M M Nöthen; P Franke; W Maier; H Beckmann; P Propping
Journal:  Am J Med Genet       Date:  1997-04-18

6.  Schedule for Affective Disorders and Schizophrenia--Lifetime Version modified for the study of anxiety disorders (SADS-LA): rationale and conceptual development.

Authors:  S Mannuzza; A J Fyer; D F Klein; J Endicott
Journal:  J Psychiatr Res       Date:  1986       Impact factor: 4.791

7.  Failure to find DUP25 in patients with anxiety disorders, in control individuals, or in previously reported positive control cell lines.

Authors:  Melody Tabiner; Sheila Youings; Nicholas Dennis; David Baldwin; Christel Buis; Andrew Mayers; Patricia A Jacobs; John A Crolla
Journal:  Am J Hum Genet       Date:  2003-01-24       Impact factor: 11.025
  7 in total
  3 in total

Review 1.  Joint hypermobility syndrome: problems that require psychological intervention.

Authors:  C Baeza-Velasco; M C Gély-Nargeot; A Bulbena Vilarrasa; J F Bravo
Journal:  Rheumatol Int       Date:  2011-03-04       Impact factor: 2.631

Review 2.  Genomic structural variation in affective, anxiety, and stress-related disorders.

Authors:  Shinji Ono; Katharina Domschke; Jürgen Deckert
Journal:  J Neural Transm (Vienna)       Date:  2014-09-13       Impact factor: 3.575

Review 3.  Genetics of anxiety disorders.

Authors:  Paul D Arnold; Gwyneth Zai; Margaret A Richter
Journal:  Curr Psychiatry Rep       Date:  2004-08       Impact factor: 8.081
  3 in total

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