Literature DB >> 14511884

Oxytocin in prefilled Uniject injection devices for managing third-stage labor in Indonesia.

V D Tsu1, A Sutanto, K Vaidya, P Coffey, A Widjaya.   

Abstract

We assessed the use and acceptability of an injection device (Uniject) prefilled with oxytocin, as part of active management of third-stage labor (AMTL) by Indonesian midwives attending home births. We interviewed 140 village midwives (bidan di desa) and 2220 mothers whose deliveries they attended during the intervention period. We completed baseline and post-intervention assessments to determine their experiences and views of oxytocin Uniject use. Delivery logs and supervisory reports were reviewed. The assessment was done in three rural districts and one municipality in Lombok. Injection practices and oxytocin availability did not change dramatically, although dose accuracy, use of sterile injection equipment, and proper disposal improved when the Uniject device was used. Midwives had little difficulty using the Uniject device properly; they overwhelmingly preferred it to standard needles and syringes. Postpartum hemorrhage rates did not change substantially. Oxytocin via Uniject holds promise for safer, more convenient use of oxytocin by trained midwives attending home deliveries, thereby potentially reducing the incidence of postpartum hemorrhage.

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Year:  2003        PMID: 14511884     DOI: 10.1016/s0020-7292(03)00186-3

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  13 in total

1.  Factors associated with acute postpartum hemorrhage in low-risk women delivering in rural India.

Authors:  Stacie E Geller; Shivaprasad S Goudar; Marci G Adams; Vijaya A Naik; Ashlesha Patel; Mrutyunjaya B Bellad; Shobhana S Patted; Stanley A Edlavitch; Nancy Moss; Bhalchandra S Kodkany; Richard J Derman
Journal:  Int J Gynaecol Obstet       Date:  2008-03-04       Impact factor: 3.561

2.  Intravenous versus intramuscular prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos; Ioannis D Gallos; Argyro Papadopoulou
Journal:  Cochrane Database Syst Rev       Date:  2020-11-09

3.  Impact on postpartum hemorrhage of prophylactic administration of oxytocin 10 IU via Uniject™ by peripheral health care providers at home births: design of a community-based cluster-randomized trial.

Authors:  Cynthia K Stanton; Samuel Newton; Luke C Mullany; Patience Cofie; Charlotte Tawiah Agyemang; Edward Adiibokah; Niamh Darcy; Sadaf Khan; Alice Levisay; John Gyapong; Deborah Armbruster; Seth Owusu-Agyei
Journal:  BMC Pregnancy Childbirth       Date:  2012-06-07       Impact factor: 3.007

4.  Oxytocin in Uniject Disposable Auto-Disable Injection System versus Standard Use for the Prevention of Postpartum Hemorrhage in Latin America and the Caribbean: A Cost-Effectiveness Analysis.

Authors:  Andrés Pichon-Riviere; Demián Glujovsky; Osvaldo Ulises Garay; Federico Augustovski; Agustin Ciapponi; Magdalena Serpa; Fernando Althabe
Journal:  PLoS One       Date:  2015-06-09       Impact factor: 3.240

Review 5.  Prevention of postpartum hemorrhage in low-resource settings: current perspectives.

Authors:  Ndola Prata; Suzanne Bell; Karen Weidert
Journal:  Int J Womens Health       Date:  2013-11-13

6.  Active management of third stage of labour saves facility costs in Guatemala and Zambia.

Authors:  Judith T Fullerton; Kevin D Frick; Linda A Fogarty; Joy D Fishel; Donna M Vivio
Journal:  J Health Popul Nutr       Date:  2006-12       Impact factor: 2.000

Review 7.  Oxytocin for preventing postpartum haemorrhage (PPH) in non-facility birth settings.

Authors:  Tomas Pantoja; Edgardo Abalos; Evelina Chapman; Claudio Vera; Valentina P Serrano
Journal:  Cochrane Database Syst Rev       Date:  2016-04-14

Review 8.  Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos
Journal:  Cochrane Database Syst Rev       Date:  2018-09-22

9.  Effect on postpartum hemorrhage of prophylactic oxytocin (10 IU) by injection by community health officers in Ghana: a community-based, cluster-randomized trial.

Authors:  Cynthia K Stanton; Samuel Newton; Luke C Mullany; Patience Cofie; Charlotte Tawiah Agyemang; Edward Adiibokah; Seeba Amenga-Etego; Niamh Darcy; Sadaf Khan; Deborah Armbruster; John Gyapong; Seth Owusu-Agyei
Journal:  PLoS Med       Date:  2013-10-01       Impact factor: 11.069

10.  Pulmonary delivery of an ultra-fine oxytocin dry powder formulation: potential for treatment of postpartum haemorrhage in developing countries.

Authors:  Richard J Prankerd; Tri-Hung Nguyen; Jibriil P Ibrahim; Robert J Bischof; Gemma C Nassta; Livesey D Olerile; Adrian S Russell; Felix Meiser; Helena C Parkington; Harold A Coleman; David A V Morton; Michelle P McIntosh
Journal:  PLoS One       Date:  2013-12-23       Impact factor: 3.240

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