Literature DB >> 14511610

Effect of cavity margin shavings to ensure completeness of excision on local recurrence rates following breast conserving surgery.

L Barthelmes1, A Al Awa, D J Crawford.   

Abstract

AIMS: The presence of residual disease at the excision margin after breast conserving surgery is the most important risk factor for local recurrence. One method for assessing tumour margin involvement is to take shavings from the wall of the resulting cavity following wide excision of the lesion.
METHODS: We have reviewed our experience of shaving the margin of the cavity as our method to ensure completeness of excision.
RESULTS: Of 351 patients treated with breast conservation 61 patients had residual disease in the cavity margin biopsies. Younger age, axillary lymph node status, multi-focal tumours and high grade tumours were significantly correlated with margin involvement. In patients who had clear margins eight patients (2.8%) had developed a local recurrence at follow-up of 55 months (25-89 months).
CONCLUSIONS: In our hands the use of cavity margin shavings allows us to achieve an acceptable rate of local control.

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Mesh:

Year:  2003        PMID: 14511610     DOI: 10.1016/s0748-7983(03)00122-7

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  4 in total

1.  Technical factors, surgeon case volume and positive margin rates after breast conservation surgery for early-stage breast cancer.

Authors:  Peter J Lovrics; Sylvie D Cornacchi; Forough Farrokhyar; Anna Garnett; Vicky Chen; Slobodan Franic; Marko Simunovic
Journal:  Can J Surg       Date:  2010-10       Impact factor: 2.089

Review 2.  Cavity Shaving plus Lumpectomy versus Lumpectomy Alone for Patients with Breast Cancer Undergoing Breast-Conserving Surgery: A Systematic Review and Meta-Analysis.

Authors:  Ke Wang; Yu Ren; Jianjun He
Journal:  PLoS One       Date:  2017-01-03       Impact factor: 3.240

3.  A survey of current surgical treatment of early stage breast cancer in China.

Authors:  Xin Zhang; Ying Wang
Journal:  Oncoscience       Date:  2018-08-22

4.  HER-2 positive breast cancer is associated with an increased risk of positive cavity margins after initial lumpectomy.

Authors:  Haixia Jia; Weijuan Jia; Yaping Yang; Shunrong Li; Huiyi Feng; Jieqiong Liu; Nanyan Rao; Liang Jin; Jiannan Wu; Ru Gu; Liling Zhu; Kai Chen; Heran Deng; Yunjie Zeng; Qiang Liu; Erwei Song; Fengxi Su
Journal:  World J Surg Oncol       Date:  2014-09-20       Impact factor: 2.754

  4 in total

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