| Literature DB >> 14510445 |
Masumi Taki1, Yoshio Kato, Makoto Miyagishi, Yasuomi Takagi, Masayuki Sano, Kazunari Taira.
Abstract
A linear, covalently-closed, dumbbell-shaped DNA vector including a transcription unit is known to have both biological stability and safety and is expected to be useful for gene therapy. We established an easy, quick, and large preparative synthetic method of modified- and unmodified-dumbbell DNA using an intramolecular cyclization at the DNA termini.Mesh：
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Year: 2003 PMID： 14510445 DOI： 10.1093/nass/3.1.191
Source DB: PubMed Journal: Nucleic Acids Res Suppl