Literature DB >> 14510407

RNA interference and chemically modified siRNAs.

Muthiah Manoharan1.   

Abstract

RNA interference (RNAi) represents one of the most promising new frontiers in drug discovery. Short double-stranded RNA molecules are able to sequence-specifically inhibit expression of genes. This young technology offers both opportunities and challenges to nucleic acid chemists.

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Year:  2003        PMID： 14510407     DOI： 10.1093/nass/3.1.115

Source DB:  PubMed          Journal:  Nucleic Acids Res Suppl


  6 in total

Review 1.  Research progress on siRNA delivery with nonviral carriers.

Authors:  Yan Gao; Xin-Ling Liu; Xiao-Rong Li
Journal:  Int J Nanomedicine       Date:  2011-05-11

2.  RNA interference: a promising approach for the treatment of viral hepatitis.

Authors:  Mahsa Motavaf; Seyed Moayed Alavian
Journal:  Hepat Mon       Date:  2012-01-20       Impact factor: 0.660

3.  Competition for RISC binding predicts in vitro potency of siRNA.

Authors:  Erich Koller; Stephanie Propp; Heather Murray; Walter Lima; Balkrishen Bhat; Thaza P Prakash; Charles R Allerson; Eric E Swayze; Eric G Marcusson; Nicholas M Dean
Journal:  Nucleic Acids Res       Date:  2006-08-31       Impact factor: 16.971

4.  Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Authors:  Feng Li; Pradeep S Pallan; Martin A Maier; Kallanthottathil G Rajeev; Steven L Mathieu; Christoph Kreutz; Yupeng Fan; Jayodita Sanghvi; Ronald Micura; Eriks Rozners; Muthiah Manoharan; Martin Egli
Journal:  Nucleic Acids Res       Date:  2007-09-18       Impact factor: 16.971

Review 5.  RNAi Efficiency, Systemic Properties, and Novel Delivery Methods for Pest Insect Control: What We Know So Far.

Authors:  Mallikarjuna R Joga; Moises J Zotti; Guy Smagghe; Olivier Christiaens
Journal:  Front Physiol       Date:  2016-11-17       Impact factor: 4.566

Review 6.  Delivery of RNAi mediators.

Authors:  Lance P Ford; Masoud M Toloue
Journal:  Wiley Interdiscip Rev RNA       Date:  2010-06-03       Impact factor: 9.957
  6 in total

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