Literature DB >> 14509655

Development and anatomic localization of torsinA.

Shelley R Oberlin1, Marina Konakova, Stefan Pulst, Marie-Françoise Chesselet.   

Abstract

We have mapped the distribution of torsinA, the protein that is mutated in dystonia type 1 (DYT1), during postnatal development in rat brain. TorsinA was expressed in most brain regions at postnatal day 7, and its expression became more intense and widespread with age. The distribution of torsinA, however, showed marked age-dependent differences among regions of the cerebral cortex and hippocampus. Notably, large cholinergic interneurons of the striatum displayed intense torsin labeling between postnatal days 14 and 21, a period of intense synaptogenesis in this region.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14509655

Source DB:  PubMed          Journal:  Adv Neurol        ISSN： 0091-3952


  8 in total

1.  The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response.

Authors:  Pan Chen; Alexander J Burdette; J Christopher Porter; John C Ricketts; Stacey A Fox; Flavia C Nery; Jeffrey W Hewett; Laura A Berkowitz; Xandra O Breakefield; Kim A Caldwell; Guy A Caldwell
Journal:  Hum Mol Genet       Date:  2010-06-28       Impact factor: 6.150

Review 2.  Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia.

Authors:  K L Eskow Jaunarajs; P Bonsi; M F Chesselet; D G Standaert; A Pisani
Journal:  Prog Neurobiol       Date:  2015-02-17       Impact factor: 11.685

Review 3.  The neurobiological basis for novel experimental therapeutics in dystonia.

Authors:  Anthony M Downs; Kaitlyn M Roman; Simone A Campbell; Antonio Pisani; Ellen J Hess; Paola Bonsi
Journal:  Neurobiol Dis       Date:  2019-07-04       Impact factor: 5.996

4.  Abnormal motor function and dopamine neurotransmission in DYT1 DeltaGAG transgenic mice.

Authors:  Yu Zhao; Michael DeCuypere; Mark S LeDoux
Journal:  Exp Neurol       Date:  2008-01-19       Impact factor: 5.330

5.  Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia.

Authors:  Anthony M Downs; Xueliang Fan; Radhika F Kadakia; Yuping Donsante; H A Jinnah; Ellen J Hess
Journal:  Neurobiol Dis       Date:  2021-04-21       Impact factor: 5.996

6.  Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia.

Authors:  Giuseppe Sciamanna; Annalisa Tassone; Giuseppina Martella; Georgia Mandolesi; Francesca Puglisi; Dario Cuomo; Grazia Madeo; Giulia Ponterio; David George Standaert; Paola Bonsi; Antonio Pisani
Journal:  PLoS One       Date:  2011-09-02       Impact factor: 3.240

7.  Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments.

Authors:  Jill R Crittenden; Ann M Graybiel
Journal:  Front Neuroanat       Date:  2011-09-07       Impact factor: 3.856

8.  Current Gaps in the Understanding of the Subcellular Distribution of Exogenous and Endogenous Protein TorsinA.

Authors:  N Charles Harata
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2014-09-23
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.