Microarray analysis of p53-mediated transcription: multi-thousand piece puzzle or invitation to collective thinking.

Commentary to Global Genechip Profiling to Identify Genes Responsive to p53-Induced Growth Arrest and Apoptosis in Human Lung Carcinoma Cells. Robinson P, et al. Cancer Biol Ther 2(4):406-415; Microarray Expression Profiling of p53-Dependent Transcriptional Changes in an Immortalized Mouse Embryo Fibroblast Cell Line. Sax JK, et al. Cancer Biol Ther 2(4):416-430; and Microarray Analysis of p53 Target Gene Expression Patterns in the Spleen and Thymus in Response to Ionizing Radiation. Burns TF, et al. Cancer Biol Ther 2(4):431-443.