Literature DB >> 14508086

Farnesyl transferase inhibitors: mechanism of action, translational studies and clinical evaluation.

W Robert Bishop1, Paul Kirschmeier, Charles Baum.   

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Year:  2003        PMID： 14508086

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN： 1538-4047            Impact factor:   4.742


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  10 in total

1.  Simvastatin interacts synergistically with tipifarnib to induce apoptosis in leukemia cells through the disruption of RAS membrane localization and ERK pathway inhibition.

Authors:  Tamer A Ahmed; John Hayslip; Markos Leggas
Journal:  Leuk Res       Date:  2014-09-16       Impact factor: 3.156

2.  Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.

Authors:  Monica P Mallampalli; Gregory Huyer; Pravin Bendale; Michael H Gelb; Susan Michaelis
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-26       Impact factor: 11.205

Review 3.  Cenp-F (mitosin) is more than a mitotic marker.

Authors:  Asta Varis; Anna-Leena Salmela; Marko J Kallio
Journal:  Chromosoma       Date:  2006-03-25       Impact factor: 4.316

4.  Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation.

Authors:  Yun Dai; Payal Khanna; Shuang Chen; Xin-Yan Pei; Paul Dent; Steven Grant
Journal:  Blood       Date:  2007-01-30       Impact factor: 22.113

5.  Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.

Authors:  Irina V Lebedeva; Zhao-zhong Su; Nichollaq Vozhilla; Lejuan Chatman; Devanand Sarkar; Paul Dent; Mohammad Athar; Paul B Fisher
Journal:  Cancer Res       Date:  2008-09-03       Impact factor: 12.701

6.  The effect of the farnesyl protein transferase inhibitor SCH66336 on isoprenylation and signalling by the prostacyclin receptor.

Authors:  Sarah J O'Meara; B Therese Kinsella
Journal:  Biochem J       Date:  2005-02-15       Impact factor: 3.857

7.  Structure of protein geranylgeranyltransferase-I from the human pathogen Candida albicans complexed with a lipid substrate.

Authors:  Michael A Hast; Lorena S Beese
Journal:  J Biol Chem       Date:  2008-08-19       Impact factor: 5.157

Review 8.  Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents.

Authors:  Woo Seok Yang; Seung-Gu Yeo; Sungjae Yang; Kyung-Hee Kim; Byong Chul Yoo; Jae Youl Cho
Journal:  Amino Acids       Date:  2017-06-19       Impact factor: 3.520

9.  Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses.

Authors:  Woo Seok Yang; Han Gyung Kim; Eunji Kim; Sang Yun Han; Nur Aziz; Young-Su Yi; Sunggyu Kim; Yunmi Lee; Byong Chul Yoo; Jeung-Whan Han; Narayanan Parameswaran; Ji Hye Kim; Jae Youl Cho
Journal:  Cells       Date:  2020-05-14       Impact factor: 6.600

Review 10.  Recent Developments in Targeting RAS Downstream Effectors for RAS-Driven Cancer Therapy.

Authors:  Ozge Tatli; Gizem Dinler Doganay
Journal:  Molecules       Date:  2021-12-14       Impact factor: 4.411
  10 in total

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