Literature DB >> 1450798

Urinary collagen crosslinks reflect the radiographic severity of knee osteoarthritis.

P W Thompson1, T D Spector, I T James, E Henderson, D J Hart.   

Abstract

The collagen crosslinks deoxypyridinoline and pyridinoline are indices of mature collagen breakdown and reflect increased bone turnover. Urinary levels were found to be significantly raised in a group of 59 women with knee OA compared to 110 female controls from the general population. Levels of the crosslinks correlated significantly with X-ray grade of all subjects including women from the general population with mild, often asymptomatic, disease. These correlations were not diminished after adjustment for age and weight.

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Year:  1992        PMID: 1450798     DOI: 10.1093/rheumatology/31.11.759

Source DB:  PubMed          Journal:  Br J Rheumatol        ISSN: 0263-7103


  9 in total

1.  Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage.

Authors:  P Garnero; M Piperno; E Gineyts; S Christgau; P D Delmas; E Vignon
Journal:  Ann Rheum Dis       Date:  2001-06       Impact factor: 19.103

Review 2.  Diagnosis of osteoarthritis. Guidelines and current pitfalls.

Authors:  G Bálint; B Szebenyi
Journal:  Drugs       Date:  1996       Impact factor: 9.546

3.  Changes in (markers of) bone metabolism during high dose corticosteroid pulse treatment in patients with rheumatoid arthritis.

Authors:  W F Lems; M I Gerrits; J W Jacobs; R M van Vugt; H J van Rijn; J W Bijlsma
Journal:  Ann Rheum Dis       Date:  1996-05       Impact factor: 19.103

4.  Concentrations of pyridinoline and deoxypyridinoline in joint tissues from patients with osteoarthritis or rheumatoid arthritis.

Authors:  M Takahashi; K Kushida; H Hoshino; M Suzuki; M Sano; S Miyamoto; T Inoue
Journal:  Ann Rheum Dis       Date:  1996-05       Impact factor: 19.103

5.  Urinary type II collagen C-telopeptide levels are increased in patients with rapidly destructive hip osteoarthritis.

Authors:  P Garnero; T Conrozier; S Christgau; P Mathieu; P D Delmas; E Vignon
Journal:  Ann Rheum Dis       Date:  2003-10       Impact factor: 19.103

6.  Urinary and synovial pyridinium crosslink concentrations in patients with rheumatoid arthritis and osteoarthritis.

Authors:  L Sinigaglia; M Varenna; L Binelli; F Bartucci; M Arrigoni; R Ferrara; G Abbiati
Journal:  Ann Rheum Dis       Date:  1995-02       Impact factor: 19.103

7.  Investigation of generalized osteoarthritis by combining X-ray grading of the knee, spine and hand using biochemical markers for arthritis in patients with knee osteoarthritis.

Authors:  Masashi Abe; Masaaki Takahashi; Kenichi Naitou; Kumiko Ohmura; Akira Nagano
Journal:  Clin Rheumatol       Date:  2003-11-13       Impact factor: 2.980

8.  Biochemical markers of bone turnover in aseptic loosening in hip arthroplasty.

Authors:  Nikolaus A Streich; Tobias Gotterbarm; Martin Jung; Ulrich Schneider; Christian Heisel
Journal:  Int Orthop       Date:  2007-12-15       Impact factor: 3.075

9.  Bone mineral density and bone turnover in spinal osteoarthrosis.

Authors:  N F Peel; N A Barrington; A Blumsohn; A Colwell; R Hannon; R Eastell
Journal:  Ann Rheum Dis       Date:  1995-11       Impact factor: 19.103

  9 in total

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