| Literature DB >> 1450798 |
P W Thompson1, T D Spector, I T James, E Henderson, D J Hart.
Abstract
The collagen crosslinks deoxypyridinoline and pyridinoline are indices of mature collagen breakdown and reflect increased bone turnover. Urinary levels were found to be significantly raised in a group of 59 women with knee OA compared to 110 female controls from the general population. Levels of the crosslinks correlated significantly with X-ray grade of all subjects including women from the general population with mild, often asymptomatic, disease. These correlations were not diminished after adjustment for age and weight.Entities:
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Year: 1992 PMID: 1450798 DOI: 10.1093/rheumatology/31.11.759
Source DB: PubMed Journal: Br J Rheumatol ISSN: 0263-7103