Literature DB >> 1450726

The hepatitis B virus X protein transactivation of c-fos and c-myc proto-oncogenes is mediated by multiple transcription factors.

M L Avantaggiati1, C Balsano, G Natoli, E De Marzio, H Will, E Elfassi, M Levrero.   

Abstract

We have constructed two expression vectors in order to study the action of the HBV 17 Kd X protein on the c-fos and c-myc promoters. The results show that the promoters contain multiple elements that respond to X protein, suggesting involvement of multiple transcription factors. The exact mechanism of the interaction remains elusive, but our data allow speculation about the factors that may be influenced.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1450726     DOI: 10.1007/978-3-7091-5633-9_12

Source DB:  PubMed          Journal:  Arch Virol Suppl        ISSN: 0939-1983


  4 in total

1.  The X protein of hepatitis B virus coactivates potent activation domains.

Authors:  I Haviv; D Vaizel; Y Shaul
Journal:  Mol Cell Biol       Date:  1995-02       Impact factor: 4.272

2.  Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha.

Authors:  F Su; R J Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-05       Impact factor: 11.205

3.  Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.

Authors:  F Su; C N Theodosis; R J Schneider
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

4.  Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma.

Authors:  Alip Ghosh; Suchandrima Ghosh; Debanjali Dasgupta; Amit Ghosh; Somenath Datta; Nilabja Sikdar; Simanti Datta; Abhijit Chowdhury; Soma Banerjee
Journal:  Int J Biol Sci       Date:  2016-01-01       Impact factor: 6.580

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.