Literature DB >> 14507186

Titanocene(III)-promoted Reformatsky additions.

J D Parrish1, Daniel R Shelton, R Daniel Little.   

Abstract

[reaction: see text] A novel method for the promotion of Reformatsky-like reactions is presented. The technique employs titanocene(III) chloride as a mild and homogeneous single-electron reductant. The reactions are rapid, operationally simple, and compatible with a wide range of functionalities. These additions are also anti diastereoselective.

Entities:  

Year:  2003        PMID: 14507186     DOI: 10.1021/ol035269c

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs.

Authors:  Paul A Wender; Jenny Reuber
Journal:  Tetrahedron       Date:  2011-12-23       Impact factor: 2.457

2.  Towards the Total Synthesis of Pl-3: Preparation of the Eastern Fragment through a Diastereoselective SmI2-Mediated Reformatsky Reaction.

Authors:  Rita Fürst; Christoph Lentsch; Uwe Rinner
Journal:  European J Org Chem       Date:  2013-03-07
  2 in total

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