Literature DB >> 1450705

Induction of autoantibodies during alpha interferon treatment in chronic hepatitis B.

G Fattovich1, C Betterle, L Brollo, G Giustina, B Pedini, A Alberti.   

Abstract

Thirty-two patients with chronic hepatitis B treated with alpha interferon were tested for 12 different antibodies. Only a minority (18%) of cases developed antinuclear antibodies and none developed clinical signs of autoimmune disease. These data suggest that, at the dose regimen used, interferon therapy of chronic hepatitis B is not associated with triggering of autoimmunity.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1450705     DOI: 10.1007/978-3-7091-5633-9_65

Source DB:  PubMed          Journal:  Arch Virol Suppl        ISSN: 0939-1983


  3 in total

Review 1.  The humoral immune response in acute and chronic hepatitis B virus infection.

Authors:  D R Milich; M Sallberg; T Maruyama
Journal:  Springer Semin Immunopathol       Date:  1995

Review 2.  Cytokine-induced autoimmune disorders.

Authors:  P Miossec
Journal:  Drug Saf       Date:  1997-08       Impact factor: 5.606

Review 3.  Clinical toxicity of the interferons.

Authors:  T Vial; J Descotes
Journal:  Drug Saf       Date:  1994-02       Impact factor: 5.606

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.