Literature DB >> 14506450

[Acute Gemella haemolysans spondylodiscitis in an immunocompetent patient].

Benoît Martha1, Michel Duong, Marielle Buisson, Michèle Grappin, Lionel Piroth, Pascal Chavanet, Henri Portier.   

Abstract

INTRODUCTION: Gemella is a commensal bacterium of the upper respiratory tract responsible for rare infections such as acute endocarditis and meningitis. We report the case of an acute Gemella haemolysans spondylodiscitis. OBSERVATION: A 72 year-old woman was hospitalised for an etiological control and treatment of acute L4-L5 spondylodiscitis with epiduritis, confirmed on MRI. The clinical picture was composed of backache with shivering and alteration in general status of health. The peripheral bacteriological samples, intra-dermal reaction and brucella serology were all negative. The surgical L5 biopsy, following bacteriological enrichment, isolated Gram-positive cocci, later identified as Gemella haemolysans. The antibiogram showed good sensitivity to amoxicillin, dalacin and erythromycin, and strong resistance to aminosides. The search for a contamination point was negative. The patient rapidly improved with antibiotics combining 6 g/d of amoxicillin and 1200 mg/d of clindamycin, and the biological and clinical signs regressed. The antibiotic bi-therapy was continued for two and a half months and then relayed to amoxicillin alone for two further weeks. COMMENTS: The first descriptions of Gemella haemolysans infection were made in the seventies. Cases of infectious endocarditis were succeeded by septicaemia on cirrhosis and later a few cases of acute post-neurosurgical meningitis. In the majority of cases, a dental contamination point was found. The difficulties in its etiological diagnosis, related to the problems in identifying this germ that has similar characteristics to Streptococcus viridans, suggests that the prevalence of Gemella haemolysans infections is greatly underrated. The sensitivity profile generally observed is sensitivity to penicillins and aminosides--the association of which is synergic--, to cyclines and glycopeptides, and resistance to trimethoprime-sulfamethoxazole.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 14506450

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  6 in total

1.  Ocular infection secondary to gemella.

Authors:  Pedram Hamrah; David Ritterband; John Seedor; Richard A Eiferman
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-01-13       Impact factor: 3.117

2.  Gemella bergeriae endocarditis diagnosed by sequencing of rRNA genes in heart valve tissue.

Authors:  Sameer Elsayed; Kunyan Zhang
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

3.  Brain abscess due to Gemella haemolysans.

Authors:  Mi Ra Lee; Sang-Oh Lee; Sue-Yun Kim; Sun Mee Yang; Yiel-Hae Seo; Yong Kyun Cho
Journal:  J Clin Microbiol       Date:  2004-05       Impact factor: 5.948

4.  Meningitis due to Gemella haemolysans in a pediatric case.

Authors:  Murat Anil; Nisel Ozkalay; Mehmet Helvaci; Neval Agus; Ozlem Guler; Aysu Dikerler; Berat Kanar
Journal:  J Clin Microbiol       Date:  2007-05-16       Impact factor: 5.948

5.  Gemella haemolysans Infection in Total Hip Arthroplasty.

Authors:  Barry Rose; Parminder J S Jeer; Anthony J Spriggins
Journal:  Case Rep Orthop       Date:  2012-05-09

6.  A Rare Case of Gemella haemolysans Infection of Knee Arthroplasty.

Authors:  Kanchi Patell; Abdul Rahman Al Armashi; Francisco J Somoza-Cano; Keyvan Ravakhah; Julia Han
Journal:  Cureus       Date:  2021-08-10
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.