Literature DB >> 1450627

Sulfadiazine therapy for toxoplasmosis in heart transplant recipients decreases cyclosporine concentration.

C H Spes1, C E Angermann, H U Stempfle, K Wenke, K Theisen.   

Abstract

Toxoplasmosis may cause serious problems after organ transplantation. For treatment of active infection, pyrimethamine combined with a sulfonamide is recommended. During oral sulfadiazine therapy, a significant decrease in cyclosporine concentrations was observed in three heart transplant recipients. This interaction has not been reported previously.

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Year:  1992        PMID： 1450627     DOI： 10.1007/bf00180742

Source DB:  PubMed          Journal:  Clin Investig        ISSN： 0941-0198


  12 in total

Review 1.  An appraisal of drug interactions with Sandimmun.

Authors:  I T Cockburn; P Krupp
Journal:  Transplant Proc       Date:  1989-10       Impact factor: 1.066

2.  Serious interaction between cyclosporin A and sulphadimidine.

Authors:  D K Jones; M Hakim; J Wallwork; T W Higenbottam; D J White
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-15

3.  Endomyocardial biopsy in the diagnosis of toxoplasmic myocarditis.

Authors:  B J Luft; M Billingham; J S Remington
Journal:  Transplant Proc       Date:  1986-12       Impact factor: 1.066

4.  Cyclosporin and intravenous sulphadimidine and trimethoprim therapy.

Authors:  J Wallwork; C G McGregor; F C Wells; R Cory-Pearce; T A English
Journal:  Lancet       Date:  1983-02-12       Impact factor: 79.321

5.  [Myocarditis caused by Toxoplasma gondii and Aspergillus fumigatus after orthotopic heart transplantation].

Authors:  H Völker; M Sigmund; M Kropff; T Hürter; J Kemnitz; C J Kirkpatrick; P Hanrath
Journal:  Z Kardiol       Date:  1991-05

6.  Toxoplasmosis and heart transplantation.

Authors:  R E Holliman; J D Johnson; S Adams; J R Pepper
Journal:  J Heart Lung Transplant       Date:  1991 Jul-Aug       Impact factor: 10.247

7.  Toxoplasmosis in heart and heart and lung transplant recipients.

Authors:  T G Wreghitt; M Hakim; J J Gray; A H Balfour; P G Stovin; S Stewart; J Scott; T A English; J Wallwork
Journal:  J Clin Pathol       Date:  1989-02       Impact factor: 3.411

8.  [Effect of enalapril, furosemide and verapamil on cyclosporin concentration in whole blood].

Authors:  C H Spes; C E Angermann; M Anthuber; B M Kemkes; K Theisen
Journal:  Klin Wochenschr       Date:  1988-12-01

9.  Primary and reactivated toxoplasma infection in patients with cardiac transplants. Clinical spectrum and problems in diagnosis in a defined population.

Authors:  B J Luft; Y Naot; F G Araujo; E B Stinson; J S Remington
Journal:  Ann Intern Med       Date:  1983-07       Impact factor: 25.391

10.  Toxoplasmosis of donor and recipient hearts after heterotopic cardiac transplantation.

Authors:  A G Rose; C J Uys; D Novitsky; D K Cooper; C N Barnard
Journal:  Arch Pathol Lab Med       Date:  1983-07       Impact factor: 5.534
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  1 in total

Review 1.  Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders.

Authors:  Diana Faulds; Karen L Goa; Paul Benfield
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546
  1 in total

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