Literature DB >> 14505563

The secret life of histones.

David A F Gillespie1, Karen H Vousden.   

Abstract

Recent evidence reveals an unexpected role for the linker histone H1.2 in DNA damage-induced apoptosis. DNA double strand breaks induce translocation of nuclear H1.2 to the cytoplasm, where it promotes release of cytochrome c from mitochondria by activating the Bcl-2 family protein, Bak.

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Year:  2003        PMID： 14505563     DOI： 10.1016/s0092-8674(03)00723-2

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  3 in total

1.  Assaying pharmacodynamic endpoints with targeted therapy: flavopiridol and 17AAG induced dephosphorylation of histone H1.5 in acute myeloid leukemia.

Authors:  Liwen Wang; Sean W Harshman; Shujun Liu; Chen Ren; Hua Xu; Larry Sallans; Michael Grever; John C Byrd; Guido Marcucci; Michael A Freitas
Journal:  Proteomics       Date:  2010-12       Impact factor: 3.984

Review 2.  Molecular and Cellular Functions of the Linker Histone H1.2.

Authors:  Shuting Lai; Jin Jia; Xiaoyu Cao; Ping-Kun Zhou; Shanshan Gao
Journal:  Front Cell Dev Biol       Date:  2022-01-11

3.  Altered expression of nuclear and cytoplasmic histone H1 in pulmonary artery and pulmonary artery smooth muscle cells in patients with IPAH.

Authors:  Megha Talati; Erin Seeley; Kaori Ihida-Stansbury; Horace Delisser; Hayes McDonald; Fei Ye; Xueqiong Zhang; Yu Shyr; Richard Caprioli; Barbara Meyrick
Journal:  Pulm Circ       Date:  2012-07       Impact factor: 3.017
  3 in total

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