Literature DB >> 14504339

Fatigue in MS is related to sympathetic vasomotor dysfunction.

P Flachenecker1, A Rufer, I Bihler, C Hippel, K Reiners, K V Toyka, J Kesselring.   

Abstract

The authors studied standard autonomic function tests and measures of heart rate variability in 60 patients with multiple sclerosis (MS) and correlated results with the Fatigue Severity Scale and the Modified Fatigue Impact Scale. The authors found that autonomic responses correlated with fatigue resembling a hypoadrenergic orthostatic response, possibly due to a sympathetic vasomotor lesion with intact vagal heart control. Treatments to control sympathetic dysfunction for MS-associated fatigue deserve further study.

Entities:  

Mesh：

Year:  2003        PMID： 14504339     DOI： 10.1212/01.wnl.0000080365.95436.b8

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  36 in total

1.  Metaboreflex activity in multiple sclerosis patients.

Authors:  Elisabetta Marongiu; Sergio Olla; Sara Magnani; Girolamo Palazzolo; Irene Sanna; Filippo Tocco; Maura Marcelli; Andrea Loi; Francesco Corona; Gabriele Mulliri; Alberto Concu; Antonio Crisafulli
Journal:  Eur J Appl Physiol       Date:  2015-10-01       Impact factor: 3.078

2.  Abnormal baroreflex responses in multiple sclerosis.

Authors:  Peter Flachenecker; Karlheinz Reiners
Journal:  Clin Auton Res       Date:  2005-12       Impact factor: 4.435

3.  Four year follow up of fatigue in a geographically defined primary biliary cirrhosis patient cohort.

Authors:  D E J Jones; N Bhala; J Burt; J Goldblatt; M Prince; J L Newton
Journal:  Gut       Date:  2005-11-18       Impact factor: 23.059

Review 4.  Cardiovascular Autonomic Dysfunction: Link Between Multiple Sclerosis Osteoporosis and Neurodegeneration.

Authors:  Zohara Sternberg
Journal:  Neuromolecular Med       Date:  2018-02-10       Impact factor: 3.843

5.  Biological outcome measurements for behavioral interventions in multiple sclerosis.

Authors:  Anja Fischer; Christoph Heesen; Stefan M Gold
Journal:  Ther Adv Neurol Disord       Date:  2011-07       Impact factor: 6.570

6.  Unveiling the relationship between autonomic involvement, fatigue, and cognitive dysfunction in early relapsing-remitting multiple sclerosis.

Authors:  Alessandro Dinoto; Sara Baldini; Maria Elisa Morelli; Fulvio Pasquin; Alessio Bratina; Antonio Bosco; Arianna Sartori; Paolo Manganotti
Journal:  Neurol Sci       Date:  2021-08-02       Impact factor: 3.307

7.  Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis.

Authors:  Khalil Kanjwal; Beverly Karabin; Yousuf Kanjwal; Blair P Grubb
Journal:  Int J Med Sci       Date:  2010-03-11       Impact factor: 3.738

Review 8.  Fatigue in neuromuscular disorders: focus on Guillain-Barré syndrome and Pompe disease.

Authors:  J M de Vries; M L C Hagemans; J B J Bussmann; A T van der Ploeg; P A van Doorn
Journal:  Cell Mol Life Sci       Date:  2010-03       Impact factor: 9.261

9.  Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease.

Authors:  Julia L Newton; Jessie Pairman; Katharine Wilton; David E J Jones; Christopher Day
Journal:  Clin Auton Res       Date:  2009-12       Impact factor: 4.435

Review 10.  Impaired Neurovisceral Integration of Cardiovascular Modulation Contributes to Multiple Sclerosis Morbidities.

Authors:  Zohara Sternberg
Journal:  Mol Neurobiol       Date:  2016-01-07       Impact factor: 5.590
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.