Literature DB >> 1450213

In vivo phospholipid modification induces changes in microsomal delta 5-desaturase activity.

A I Leikin1, R R Brenner.   

Abstract

The phospholipid composition of rat-liver microsomes was modified by feeding weaning rats a choline-free diet. After 21 days, the phosphatidylcholine content decreased with a concomitant increment of phosphatidylserine and cholesterol. The bulk fluidity of the membrane decreased. Under these conditions, the delta 5-desaturase activity was diminished as well as the arachidonic-acid content of the membrane lipids.

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Year:  1992        PMID: 1450213     DOI: 10.1016/0005-2760(92)90186-y

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  4 in total

1.  Correlation of suppressed linoleic acid metabolism with the hypocholesterolemic action of eritadenine in rats.

Authors:  K Sugiyama; A Yamakawa; S Saeki
Journal:  Lipids       Date:  1997-08       Impact factor: 1.880

2.  Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats.

Authors:  K Sugiyama; A Kumazawa; H Zhou; S Saeki
Journal:  Lipids       Date:  1998-03       Impact factor: 1.880

3.  Dietary eritadenine-induced alteration of molecular species composition of phospholipids in rats.

Authors:  K Sugiyama; A Yamakawa
Journal:  Lipids       Date:  1996-04       Impact factor: 1.880

4.  Effects of dietary protein and cholesterol on phosphatidylcholine and phosphatidylethanolamine molecular species in mouse liver.

Authors:  K Koba; L A Rozee; D F Horrobin; Y S Huang
Journal:  Lipids       Date:  1994-01       Impact factor: 1.880

  4 in total

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