Michele St Martin1, Samuel C Levine. 1. Department of Otolaryngology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Abstract
PURPOSE OF REVIEW: Chordomas are rare congenital tumors of the midline skull base. They are slow-growing and usually cause symptoms only when they compress a cranial nerve. RECENT FINDINGS: The MRI will show the lesion with irregular uptake of gadolinium. The only way to define the diagnosis is with tissue, and there are two primary pathologic forms of the disease. Resection approaches vary with extent of disease, surgeon preference, and critical structures involved. SUMMARY: There is building evidence that proton beam therapy improves survival and duration of a disease-free state.
PURPOSE OF REVIEW: Chordomas are rare congenital tumors of the midline skull base. They are slow-growing and usually cause symptoms only when they compress a cranial nerve. RECENT FINDINGS: The MRI will show the lesion with irregular uptake of gadolinium. The only way to define the diagnosis is with tissue, and there are two primary pathologic forms of the disease. Resection approaches vary with extent of disease, surgeon preference, and critical structures involved. SUMMARY: There is building evidence that proton beam therapy improves survival and duration of a disease-free state.
Authors: Seong Min Kim; Hyun Wook Park; Moon Sun Park; Seung Young Chung; Ki Seok Park; Do Sung Lee; Jung Tae Oh Journal: Brain Tumor Res Treat Date: 2013-10-31
Authors: Murat Akyol; Umut Varol; Ibrahim Yildiz; Ibrahim Vedat Bayoglu; Yasar Yildiz; Lutfiye Demir; Ahmet Dirican; Alper Can; Suna Cokmert; Mine Tunakan Oztop; Ahmet Alacacioglu; Yuksel Kucukzeybek; Mustafa Oktay Tarhan Journal: Case Rep Oncol Med Date: 2014-06-11