Literature DB >> 14501623

Relapsing upper bleeding in non-Hodgkin's oesophageal lymphoma associated with achalasia.

Andrés J del Pozo García1, Luisa García Buey, Ignacio Llorca, Teresa Iscar, Montserrat Barxias, José Cantero Perona, José M Pajares.   

Abstract

Achalasia is a disease of unknown origin in which there is a denervation of the myenteric plexus on the smooth muscle of the lower oesophageal sphincter, causing a cardial stenosis and a loss of efficacy of oesophageal peristalsis. The predominant symptoms are dysphagia for solids and liquids and regurgitation of the retained food. Occasionally, there may be oesophageal haemorrhage as a consequence of oesophagitis and stasis ulcers. An important but uncommon complication is the development of oesophageal cancer, which is typically squamous cell carcinoma. We report an exceptional case of a 77-year-old woman with a long-term achalasia and mega-oesophagus who presented four episodes of upper gastrointestinal bleeding in a 2 month period. The patient underwent surgical resection of the 10 cm of distal oesophagus, performing a partial fundoplication, and the pathological study revealed an oesophageal infiltration by a low-grade non-Hodgkin's lymphoma. After an insidious outcome, she died on the 47th day after admission.

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Year:  2003        PMID: 14501623     DOI: 10.1097/00042737-200310000-00011

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  3 in total

1.  Black oesophagus: a rare disorder with potentially fatal outcome. A forensic pathological approach based on five autopsy cases.

Authors:  M Tsokos; H Herbst
Journal:  Int J Legal Med       Date:  2005-02-03       Impact factor: 2.686

2.  Massive esophageal bleeding in long-standing achalasia complicated by esophageal carcinoma and aspirin-induced stasis ulcer: Case report.

Authors:  Joon Hyun Cho
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

3.  A Rare Case of a Life-Threatening Massive Upper Gastrointestinal Bleed and Airway Obstruction in a Patient With a Megaesophagus Secondary to Longstanding Achalasia.

Authors:  Raghav Bassi; Yasir Saeed
Journal:  Cureus       Date:  2021-02-07
  3 in total

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