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Literature DB >> 14492831

Stimulation of intestinal nervous elements by angiotensin.

Abstract

The stimulation of nervous elements in the intestine by the polypeptide angiotensin has been examined. Comparisons between nicotine, a neurotropic agent, acetylcholine which exerts principally a musculotropic action and angiotensin have been made by examining their interactions with hexamethonium and the anticholinesterase 1,5-di-(p-N-allyl-N-methylaminophenyl)pentan-3-one dibromide in both the rabbit and guinea-pig ileum. The effect of atropine on the responses of the guinea-pig ileum and botulinum toxin on the responses of the rabbit ileum to angiotensin was also tested. The results show that angiotensin causes most of its contractile response in both the guinea-pig and rabbit ileum by an indirect action, through the stimulation of nervous tissue.

Entities: Chemical Species

Keywords: HYPERTENSIN/pharmacology; INTESTINES/pharmacology

Mesh：

Substances：

Year: 1962 PMID： 14492831 PMCID： PMC1482242 DOI： 10.1111/j.1476-5381.1962.tb01423.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

15 in total

1. Comparison of the effects of inhibition of external, internal and total acetylcholinesterase upon ganglionic transmission.

Authors: R J McISAAC; G B KOELLE
Journal: J Pharmacol Exp Ther Date: 1959-05 Impact factor: 4.030

2. Classification of intestinomotor drugs by means of type D botulinum toxin.

Authors: N AMBACHE; A W LESSIN
Journal: J Physiol Date: 1955-03-28 Impact factor: 5.182

3. On the pharmacology of synthetic hypertensine.

Authors: A BIANCHI; A F DE SCHAEPDRYVER; G R DE VLEESCHHOUWER; P PREZIOSI
Journal: Arch Int Pharmacodyn Ther Date: 1960-02-01

4. The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons.

Authors: G B KOELLE
Journal: J Pharmacol Exp Ther Date: 1955-06 Impact factor: 4.030

5. Synthesis and pharmacology of the octapeptide angiotonin.

Authors: F M BUMPUS; H SCHWARZ; I H PAGE
Journal: Science Date: 1957-05-03 Impact factor: 47.728

6. The use and limitations of atropine for pharmacological studies on autonomic effectors.

Authors: N AMBACHE
Journal: Pharmacol Rev Date: 1955-12 Impact factor: 25.468

7. Autonomic ganglionic stimulants.

Authors: N AMBACHE
Journal: Arch Int Pharmacodyn Ther Date: 1954-04-01

8. The effects of nicotine on the blood vessels of skeletal muscle in the cat; an investigation of vasomotor axon reflexes.

Authors: S M HILTON
Journal: J Physiol Date: 1954-02-26 Impact factor: 5.182

9. Unmasking, after cholinergic paralysis by botulinum toxin, of a reversed action of nicotine on the mammalian intestine, revealing the probable presence of local inhibitory ganglion cells in the enteric plexuses.

Authors: N AMBACHE
Journal: Br J Pharmacol Chemother Date: 1951-03

10. The action of botulinum toxin on the neuro-muscular junction.

Authors: A S V BURGEN; F DICKENS; L J ZATMAN
Journal: J Physiol Date: 1949-08 Impact factor: 5.182

18 in total

1. A further investigation into the energy dependence of angiotensin II-induced contractions of isolated smooth muscle preparations.

Authors: A D Crocker; K A Wilson
Journal: Br J Pharmacol Date: 1975-01 Impact factor: 8.739

9. Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.

Authors: A B Hawcock; J C Barnes
Journal: Br J Pharmacol Date: 1993-04 Impact factor: 8.739

10. Effect of indomethacin and prostaglandin on the smooth muscle contracting activity of angiotensin and other agonists.

Authors: J Aboulafia; G B Mendes; M E Miyamoto; A C Paiva; T B Paiva
Journal: Br J Pharmacol Date: 1976-10 Impact factor: 8.739

Stimulation of intestinal nervous elements by angiotensin.

1. Comparison of the effects of inhibition of external, internal and total acetylcholinesterase upon ganglionic transmission.

2. Classification of intestinomotor drugs by means of type D botulinum toxin.

3. On the pharmacology of synthetic hypertensine.

4. The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons.

5. Synthesis and pharmacology of the octapeptide angiotonin.

6. The use and limitations of atropine for pharmacological studies on autonomic effectors.

7. Autonomic ganglionic stimulants.

8. The effects of nicotine on the blood vessels of skeletal muscle in the cat; an investigation of vasomotor axon reflexes.

9. Unmasking, after cholinergic paralysis by botulinum toxin, of a reversed action of nicotine on the mammalian intestine, revealing the probable presence of local inhibitory ganglion cells in the enteric plexuses.

10. The action of botulinum toxin on the neuro-muscular junction.

1. A further investigation into the energy dependence of angiotensin II-induced contractions of isolated smooth muscle preparations.

2. ANGIOTENSIN AND PERIPHERAL SYMPATHETIC NERVE ACTIVITY.

3. AN ISOLATED PREPARATION WITH A SELECTIVE SENSITIVITY TO VASOPRESSIN.

4. [Angiotensin].

5. Effect of some drugs on human umbilical artery in vitro.

6. The action of angiotensin II on guinea-pig ileum and its modification by changes in sodium concentration.

7. Mesenteric microcirculation in rats with experimental hypertension.

8. The action of angiotensin on the human colon in vitro.

9. Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.

10. Effect of indomethacin and prostaglandin on the smooth muscle contracting activity of angiotensin and other agonists.