Literature DB >> 14490984

Effects of nicorine, nornicotine and allylnornicotine on the diuretic response to water in rats.

A H REES, H SCHNIEDEN.   

Abstract

The LD50 in mice for nicotine, (-)-nornicotine and allylnornicotine given intraperitoneally was respectively 10 mg/kg, 18.8 mg/kg and 93.3 mg/kg. Whilst nicotine inhibited the renal response in rats to water, (-)-nornicotine and allylnornicotine were without effect. Nicotine antidiuresis was not antagonized by (-)-nornicotine or by allylnornicotine.

Entities:  

Keywords:  DIURESIS/experimental

Mesh：

Substances：

Year:  1962        PMID： 14490984      PMCID： PMC1482128          DOI： 10.1111/j.1476-5381.1962.tb01409.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  6 in total

1.  The effect of nalorphine on the antidiuretic action of morphine in rats and men.

Authors:  H SCHNIEDEN; E K BLACKMORE
Journal:  Br J Pharmacol Chemother       Date:  1955-03

2.  The effect of N-allylnormorphine upon the antidiuretic action of morphine.

Authors:  C A WINTER; C E GAFFNEY; L FLATAKER
Journal:  J Pharmacol Exp Ther       Date:  1954-07       Impact factor: 4.030

3.  The action of nervous depressants on the antidiuretic and chloruretic effect of nicotine.

Authors:  Z SUPEK; V EISEN
Journal:  Arch Int Pharmacodyn Ther       Date:  1953-02

4.  Antidiuretic Action of Nicotine.

Authors:  J H Burn; L H Truelove; I Burn
Journal:  Br Med J       Date:  1945-03-24

5.  The effects of nicotine, hexamethonium and ethanol on the secretion of the antidiuretic and oxytocic hormones of the rat.

Authors:  G W BISSET; J M WALKER
Journal:  Br J Pharmacol Chemother       Date:  1957-12

6.  The effect of levallorphan tartrate and of adiphenine hydrochloride on the antidiuretic action of morphine and nicotine.

Authors:  H SCHNIEDEN
Journal:  Br J Pharmacol Chemother       Date:  1960-12
  6 in total

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