Literature DB >> 14489640

Pyrimidine metabolism in man. V. The measurement in vivo of the biochemical effect of antineoplastic agents in animal and human subjects.

M T RABKIN, E W FREDERICK, M LOTZ, L H SMITH.   

Abstract

Entities:  

Keywords:  ANTIMETABOLITES/pharmacology; ANTINEOPLASTIC AGENTS/pharmacology; CARBON DIOXIDE/metabolism; NUCLEOSIDES AND NUCLEOTIDES/metabolism; PYRIMIDINES/metabolism

Mesh：

Substances：

Year:  1962        PMID： 14489640      PMCID： PMC290989          DOI： 10.1172/JCI104544

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


× No keyword cloud information.
  31 in total

1.  Purine analogs as feedback inhibitors.

Authors:  J S GOTS; E G GOLLUB
Journal:  Proc Soc Exp Biol Med       Date:  1959 Aug-Sep

2.  Orotidylic acid decarboxylase: inhibition studies with azauridine 5'-phosphate.

Authors:  R E HANDSCHUMACHER
Journal:  J Biol Chem       Date:  1960-10       Impact factor: 5.157

3.  Biosynthesis of diphosphopyridine nucleotide. III. Nicotinic acid mononucleotide pyrophos-phorylase.

Authors:  J IMSANDE; P HANDLER
Journal:  J Biol Chem       Date:  1961-02       Impact factor: 5.157

4.  Pyrimidine metabolism in man. I. The biosynthesis of orotic acid.

Authors:  L H SMITH; F A BAKER
Journal:  J Clin Invest       Date:  1959-05       Impact factor: 14.808

5.  In vivo sensitivity of normal and neoplastic mouse tissues to azaserine.

Authors:  E C MOORE; G A LEPAGE
Journal:  Cancer Res       Date:  1957-09       Impact factor: 12.701

6.  Studies of ribose metabolism. V. Factors influencing in vivo ribose synthesis in the rat.

Authors:  H H HIATT
Journal:  J Clin Invest       Date:  1958-10       Impact factor: 14.808

7.  Pyrimidine metabolism. I. Enzymatic pathways of uracil and thymine degradation.

Authors:  E S CANELLAKIS
Journal:  J Biol Chem       Date:  1956-07       Impact factor: 5.157

8.  [Demecolcin (substance F) a new alkaloid with strong antimitotic effect isolated from Colchicum autumnale].

Authors:  B SCHAR; P LOUSTALOT; F GROSS
Journal:  Klin Wochenschr       Date:  1954-01-15

9.  A survey of the metabolism of orotic acid in the rat.

Authors:  R B HURLBERT; V R POTTER
Journal:  J Biol Chem       Date:  1952-03       Impact factor: 5.157

10.  Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo.

Authors:  N K CHAUDHURI; B J MONTAG; C HEIDELBERGER
Journal:  Cancer Res       Date:  1958-04       Impact factor: 12.701
View more
  7 in total

1.  THE EFFECT OF 6-AZAURIDINE ADMINISTRATION ON DE NOVO PYRIMIDINE PRODUCTION IN CHRONIC MYELOGENOUS LEUKEMIA.

Authors:  V H BONO; S M WEISSMAN; E FREI
Journal:  J Clin Invest       Date:  1964-07       Impact factor: 14.808

2.  Studies on the control of pyrimidine biosynthesis in human diploid cell strains, I. Effect of 6-azauridine on cellular phenotype.

Authors:  L Pinsky; R S Krooth
Journal:  Proc Natl Acad Sci U S A       Date:  1967-04       Impact factor: 11.205

3.  Studies on the control of pyrimidine biosynthesis in human diploid cell strains. II. Effects of 5-azaorotic acid, barbituric acid, and pyrimidine precursors on cellular phenotype.

Authors:  L Pinsky; R S Krooth
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205

4.  The conversion of orotic acid into uridine 5'-monophosphate by isolated perfused normal and regenerating rat livers.

Authors:  N Fausto
Journal:  Biochem J       Date:  1972-10       Impact factor: 3.857

5.  Urinary polypeptides related to collagen synthesis.

Authors:  S M Krane; A J Muñoz; E D Harris
Journal:  J Clin Invest       Date:  1970-04       Impact factor: 14.808

6.  Mechanism of allopurinol-mediated increase in enzyme activity in man.

Authors:  T D Beardmore; J S Cashman; W N Kelley
Journal:  J Clin Invest       Date:  1972-07       Impact factor: 14.808

7.  Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity.

Authors:  Jian-Long Li; Wei Zhao; Chen Zhou; Ya-Xuan Zhang; Hong-Mei Li; Ya-Ling Tang; Xin-Hua Liang; Tao Chen; Ya-Jie Tang
Journal:  Sci Rep       Date:  2015-10-07       Impact factor: 4.379
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.