| Literature DB >> 1447952 |
K Kubota1, H Kurabayashi, K Tamura, E Kawada, J Tamura, T Shirakura.
Abstract
To clarify the mechanism of the intoxicating feeling attained after a traditional 47 degrees C hot-spring bath called 'jikan-yu' in Kusatsu-spa, Japan, we examined the change in plasma levels of beta-endorphin and methionine enkephalin in 7 healthy subjects. The mean sublingual temperature rose from 36.8 degrees C to 38.6 degrees C and the plasma beta-endorphin level from 16.2 pg/ml to 49.5 pg/ml 2 minutes after completing a 3-minute bath in 47 degrees C hot-spring water. However, the plasma methionine enkephalin level was not changed. This feeling of intoxication may be explained by the transient rise in plasma beta-endorphin level.Entities:
Mesh:
Substances:
Year: 1992 PMID: 1447952 DOI: 10.1016/0024-3205(92)90039-r
Source DB: PubMed Journal: Life Sci ISSN: 0024-3205 Impact factor: 5.037