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Literature DB >> 1447903

The use of non-steroidal anti-inflammatory drugs for the relief of pain in laboratory rodents and rabbits.

Abstract

The data concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs) and evidence for their efficacy in laboratory rats and mice are reviewed. This information is then extrapolated to clinical situations and dose rates that take account of ulcerogenic side effects are recommended. NSAIDs have the potential to be a very useful group of analgesics and should always be considered when attempting to provide pain relief in laboratory animals.

Entities: Disease Species

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Year: 1992 PMID： 1447903 DOI： 10.1258/002367792780745706

Source DB: PubMed Journal: Lab Anim ISSN： 0023-6772 Impact factor: 2.471

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Cited

16 in total

1. Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy.

Authors: C R Atchison; A Balakumaran; A B West; W E Hoffmann; M Treinen-Moslen
Journal: Dig Dis Sci Date: 2000-03 Impact factor: 3.199

2. A model for clinical evaluation of perioperative analgesia in rabbits (Oryctolagus cuniculus).

Authors: Lara A Weaver; Cheryl A Blaze; Deborah E Linder; Karl A Andrutis; Alicia Z Karas
Journal: J Am Assoc Lab Anim Sci Date: 2010-11 Impact factor: 1.232

3. Efficacy of various analgesics on shoulder function and rotator cuff tendon-to-bone healing in a rat (Rattus norvegicus) model.

Authors: Adam C Caro; Jennica J Tucker; Sarah M Yannascoli; Andrew A Dunkman; Stephen J Thomas; Louis J Soslowsky
Journal: J Am Assoc Lab Anim Sci Date: 2014-03 Impact factor: 1.232

Review 4. Predictive validity of behavioural animal models for chronic pain.

Authors: Odd-Geir Berge
Journal: Br J Pharmacol Date: 2011-10 Impact factor: 8.739

5. Postsurgical food and water consumption, fecal corticosterone metabolites, and behavior assessment as noninvasive measures of pain in vasectomized BALB/c mice.

Authors: Kirsten R Jacobsen; Otto Kalliokoski; Anne C Teilmann; Jann Hau; Klas Sp Abelson
Journal: J Am Assoc Lab Anim Sci Date: 2012-01 Impact factor: 1.232

The use of non-steroidal anti-inflammatory drugs for the relief of pain in laboratory rodents and rabbits.

1. Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy.

2. A model for clinical evaluation of perioperative analgesia in rabbits (Oryctolagus cuniculus).

3. Efficacy of various analgesics on shoulder function and rotator cuff tendon-to-bone healing in a rat (Rattus norvegicus) model.

Review 4. Predictive validity of behavioural animal models for chronic pain.

5. Postsurgical food and water consumption, fecal corticosterone metabolites, and behavior assessment as noninvasive measures of pain in vasectomized BALB/c mice.

6. Palatability and treatment efficacy of various ibuprofen formulations in C57BL/6 mice with ulcerative dermatitis.

7. Effects of indomethacin and buprenorphine analgesia on the postoperative recovery of mice.

8. Two pathways for cyclooxygenase-2 protein degradation in vivo.

9. Preparation and In Vitro Evaluation of Ibuprofen Spherical Agglomerates.

10. Self-Emulsifying Formulation of Indomethacin with Improved Dissolution and Oral Absorption.