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Literature DB >> 14472535

Chronic infusion of tritiated thymidine into mice with tumors.

Abstract

A technique for the chronic infusion of mice is presented. Infusion of tritiated thymidine for 3 to 7 days labels most, but not all, of the cells of autochthonous breast tumors. Many of the unlabeled tumor cells are probably nonproliferating, but some may represent cells with exceptionally long intermitotic times.

Entities: Chemical Disease Species

Keywords: NEOPLASMS/experimental; NUCLEOSIDES AND NUCLEOTIDES/metabolism; TRITIUM/metabolism

Mesh：

Substances：

Year: 1962 PMID： 14472535 DOI： 10.1126/science.135.3499.213

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

14 in total

1. 5-FLUOROURACIL TREATMENT OF LIVER METASTASES BY CONTINUOUS HEPATIC ARTERY INFUSION VIA COURNAND CATHETER: RESULTS AND SUITABILITY FOR INTENSIVE POSTSURGICAL ADJUVANT CHEMOTHERAPY.

Authors: M J BRENNAN; R W TALLEY; E H DRAKE; V K VAITKEVICIUS; A K POZNANSKI; B E BRUSH
Journal: Ann Surg Date: 1963-09 Impact factor: 12.969

2. Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model.

Authors: Patrick C Hettinger; Rupeng Li; Ji-Geng Yan; Hani S Matloub; Younghoon R Cho; Christopher P Pawela; Daniel B Rowe; James S Hyde
Journal: J Neurosci Methods Date: 2011-06-24 Impact factor: 2.390

3. [DNA and RNA synthesis in benign and malignant lymphomas].

Authors: H Theml; F Trepel; J Rastetter; H Begemann
Journal: Klin Wochenschr Date: 1967-06-15

4. Combination cancer chemotherapy by regional intra-arterial or intra-aortic infusion of 5-fluorouracil and mitomycin-C with or without irradiation.

Authors: T Miura; M Ishida; S Hatano
Journal: Jpn J Surg Date: 1971-06

9. The tumor dormant state. Quantitation of L5178Y cells and host immune responses during the establishment and course of dormancy in syngeneic DBA/2 mice.

Authors: K J Weinhold; L T Goldstein; E F Wheelock
Journal: J Exp Med Date: 1979-03-01 Impact factor: 14.307

10. THE REPLICATION TIME AND PATTERN OF CARCINOGEN--INDUCED HEPATOMA CELLS.

Authors: J POST; J HOFFMAN
Journal: J Cell Biol Date: 1964-08 Impact factor: 10.539

Chronic infusion of tritiated thymidine into mice with tumors.

1. 5-FLUOROURACIL TREATMENT OF LIVER METASTASES BY CONTINUOUS HEPATIC ARTERY INFUSION VIA COURNAND CATHETER: RESULTS AND SUITABILITY FOR INTENSIVE POSTSURGICAL ADJUVANT CHEMOTHERAPY.

2. Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model.

3. [DNA and RNA synthesis in benign and malignant lymphomas].

4. Combination cancer chemotherapy by regional intra-arterial or intra-aortic infusion of 5-fluorouracil and mitomycin-C with or without irradiation.

5. [Cell proliferation in normal and malignant tissues: H3-thymidine incorporation in vitro under standard conditions].

6. Characterization of the cell kinetics and growth properties of cystic fibrosis diploid fibroblasts in vitro.

7. Evaluation of growth hormone production from GH1 cells in vitro: effect of culture media and time in culture.

8. Autoradiographic investigations about the proliferation rate in different areas of human head and neck carcinomas.

9. The tumor dormant state. Quantitation of L5178Y cells and host immune responses during the establishment and course of dormancy in syngeneic DBA/2 mice.

10. THE REPLICATION TIME AND PATTERN OF CARCINOGEN--INDUCED HEPATOMA CELLS.