Literature DB >> 14467694

Neurochemical differences between two strains of mice.

J W MAAS.   

Abstract

Microanalytic determinations of serotonin and norepinephrine were done on dissected portions of brain consisting of diencephalon, mesencephalon, and pons in two strains of mice, C57 bl/10 and BALB/c. The BALB/c strain had 1.34 microg of serotonin per gram of dissected brain, and the C57 bl/10 had 1.07 microg/g. This difference was statistically significant (P < 0.01). The levels of norepinephrine were not significantly different in the two strains (P > 0.25).

Entities:  

Keywords:  BRAIN/chemistry; MICE; NOREPINEHRINE/chemistry; SEROTONIN/chemistry

Mesh:

Substances:

Year:  1962        PMID: 14467694     DOI: 10.1126/science.137.3530.621

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  11 in total

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10.  Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.

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