Literature DB >> 14460984

Antibody production in human malaria as determined by the fluorescent antibody technique.

S F KUVIN, J E TOBIE, C B EVANS, G R COATNEY, P G CONTACOS.   

Abstract

No reliable serological test has been available in the past to follow the course of antibody production in malarial infections. The indirect method of immunofluorescence was utilized in this investigation to study antibody response to sporozoite-induced Plasmodium vivax infections in two human volunteers. Malarial antibody was demonstrated approximately 3 weeks after infection, and has persisted thus far for 121 days. These preliminary results suggest that this method of serological testing is specific and provides a sensitive means of titrating antibody produced in malarial infections.

Entities:  

Keywords:  ANTIBODIES; MALARIA/immunology

Mesh：

Substances：

Year:  1962        PMID： 14460984     DOI： 10.1126/science.135.3509.1130

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  FLUORESCENT ANTIBODY METHODS AND THEIR USE IN MALARIA RESEARCH.

Authors:  A VOLLER
Journal:  Bull World Health Organ       Date:  1964       Impact factor: 9.408

2.  MALARIAL ANTIBODY TITRES OF WEST AFRICANS IN BRITAIN.

Authors:  S F KUVIN; A VOLLER
Journal:  Br Med J       Date:  1963-08-24

3.  [The value of the immunofluorescent reaction in the detection of asymptomatic parasitemia due to Plasmodium malariae].

Authors:  G Lupascu; A Bossie-Agavriloaei; C Bona; L Ioanid; M Smolinski
Journal:  Bull World Health Organ       Date:  1967       Impact factor: 9.408

4.  Indirect fluorescent antibody test for malaria antibody.

Authors:  W A Sodeman; G M Jeffery
Journal:  Public Health Rep       Date:  1966-11       Impact factor: 2.792

5.  Malarial antigen from human brain.

Authors:  A I Williams; H McFarlane
Journal:  Clin Exp Immunol       Date:  1968-11       Impact factor: 4.330

6.  Distribution of malarial antibody in maternal and cord sera.

Authors:  A I Williams; H McFarlane
Journal:  Arch Dis Child       Date:  1969-08       Impact factor: 3.791

7.  [Serological evolution of infection by Plasmodium malariae: variations of fluorescent antibody titre after radical treatment].

Authors:  G Lupascu; A Bossie-Agavriloaei; L Ioanid; C Bona; M Smolinski; E Negulici; C Florescu
Journal:  Bull World Health Organ       Date:  1969       Impact factor: 9.408

8.  Plasmodium gallinaceum as antigen in the diagnosis of human malaria.

Authors:  A Kielmann; N Weiss; G Sarasin
Journal:  Bull World Health Organ       Date:  1970       Impact factor: 9.408

9.  Monoclonal antibodies to stage-specific, species-specific, and cross-reactive antigens of the rodent malarial parasite, Plasmodium yoelii.

Authors:  D W Taylor; K J Kim; P A Munoz; C B Evans; R Asofsky
Journal:  Infect Immun       Date:  1981-05       Impact factor: 3.441

10.  Studies on the relationship between fluorescent antibody response and ecology of malaria in Malaysia.

Authors:  W E Collins; M Warren; J C Skinner; H J Fredericks
Journal:  Bull World Health Organ       Date:  1968       Impact factor: 9.408
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