| Literature DB >> 144563 |
A K Fowler, D R Twardzik, C D Reed, O S Weislow, A Hellman.
Abstract
Freeze-thaw preparations of banded Rauscher murine leukemia virus markedly suppressed the in vitro cellular-mediated blastogenic response of murine splenic lymphocytes to phytohemagglutinin-P and to allogeneic cells in two-way mixed-leukocyte reaction. Suppression was shown not to be due to cytotoxicity or to virus-mitogen binding. It is suggested that a virion envelope component interferes with cellular-mediated immunity by altering cell recognition sites.Entities:
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Year: 1977 PMID: 144563
Source DB: PubMed Journal: Cancer Res ISSN: 0008-5472 Impact factor: 12.701