Literature DB >> 14445195

Antiphlogistic activity of iproniazid.

I SETNIKAR, M SALVATERRA, O TEMELCOU.   

Abstract

Iproniazid was found to inhibit formalin-induced oedema of the foot, dextran-induced oedema and cotton-pellet-induced granulomatous tissue in the rat. The presence of the adrenals was essential for the antiphlogistic activity. The antiphlogistic action was not accompanied by any antipyretic effect. Inhibition of formalin-induced oedema was also observed with phenylbutazone and with salicylamide.

Entities:  

Keywords:  EDEMA/experimental; INFLAMMATION/experimental; IPRONIAZID/pharmacology

Mesh：

Substances：

Year:  1959        PMID： 14445195      PMCID： PMC1481896          DOI： 10.1111/j.1476-5381.1959.tb00952.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  7 in total

1.  [Pharmacological data on p-hydroxypropiophenone sulfate].

Authors:  I SETNIKAR; W MURMANN
Journal:  Farmaco Sci       Date:  1958

2.  [Effect of serotonin on plantar edema induced by dextran in rat].

Authors:  G GEORGES; M HEROLD
Journal:  C R Seances Soc Biol Fil       Date:  1957

3.  [Effect of 5-hydroxytryptamine on pituitary adrenal function in rat].

Authors:  G GEORGES
Journal:  C R Seances Soc Biol Fil       Date:  1957

4.  The effect of marsilid in patients having rheumatoid arthritis; the theoretical causal role of certain amine oxidases.

Authors:  A L SCHERBEL
Journal:  J Clin Exp Psychopathol       Date:  1958 Apr-Jun

5.  Investigation of the synergism of isonicotinic acid hydrazide and cortisone. I. Effect of isonicotinic acid on the metabolism of cortisone by liver tissue.

Authors:  L L WIESEL
Journal:  Am J Med Sci       Date:  1956-10       Impact factor: 2.378

6.  [On the mechanism of cortisone inhibition of connective tissue proliferation].

Authors:  R MEIER; W SCHULER; P DESAULLES
Journal:  Experientia       Date:  1950-12-15

7.  Investigation of the synergism of isonicotinic acid hydrazide and cortisone. II. Long-term study of the synergistic action of isonicotinic acid hydrazide and cortisone acetate in the treatment of rheumatoid arthritis.

Authors:  A S BARRITT; C J SCHEID; L L WIESEL
Journal:  Am J Med Sci       Date:  1956-10       Impact factor: 2.378
  7 in total
  2 in total

1.  Release of prostaglandin-like substances by Shigella endotoxin and its inhibition by non-steroidal anti-inflammatory compounds.

Authors:  P Bhattacherjee
Journal:  Br J Pharmacol       Date:  1975-08       Impact factor: 8.739

2.  Some inhibitors of histamine-induced and formaldehyde-induced inflammation in mice.

Authors:  B J NORTHOVER; G SUBRAMANIAN
Journal:  Br J Pharmacol Chemother       Date:  1961-04
  2 in total

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