Literature DB >> 1444325

New hypoxanthine nucleosides with RNA antiviral activity.

V Nair1, M A Ussery.   

Abstract

A series of novel C-2 functionalized hypoxanthine and purine ribonucleosides have been synthesized and evaluated against exotic RNA viruses of the family or genus alpha, arena, flavi, and rhabdo. Both specific and broad-spectrum antiviral activities were discovered but only with hypoxanthine nucleosides.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1444325     DOI： 10.1016/0166-3542(92)90076-h

Source DB:  PubMed          Journal:  Antiviral Res        ISSN： 0166-3542            Impact factor:   5.970


  3 in total

1.  Base-functionalized carbocyclic nucleosides: design, synthesis, and mechanism of antiviral activity.

Authors:  Vasu Nair; Fan Zhang; Xiaohui Ma; Eric Bonsu
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2009-05       Impact factor: 1.381

2.  Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro.

Authors:  Stephan Günther; Marcel Asper; Christina Röser; Luciano K S Luna; Christian Drosten; Beate Becker-Ziaja; Peter Borowski; Huan-Ming Chen; Ramachandra S Hosmane
Journal:  Antiviral Res       Date:  2004-09       Impact factor: 5.970

3.  Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.

Authors:  Baole Zhang; Luping Pang; Manesh Nautiyal; Steff De Graef; Bharat Gadakh; Eveline Lescrinier; Jef Rozenski; Sergei V Strelkov; Stephen D Weeks; Arthur Van Aerschot
Journal:  Molecules       Date:  2020-10-16       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.