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Literature DB >> 1444316

Bactericidal activity of ramoplanin against antibiotic-resistant enterococci.

C C Johnson¹, S Taylor, P Pitsakis, P May, M E Levison.

Abstract

Ramoplanin, a new lipoglycodepsipeptide antibiotic, was uniformly active against 65 strains of enterococci, including strains highly resistant to vancomycin, penicillin G, and gentamicin. MBCs were usually within a fourfold dilution of the MICs. In time-kill studies, ramoplanin alone demonstrated dose-dependent bactericidal activity against enterococcal strains that resisted killing by vancomycin or penicillin in combination with gentamicin.

Entities: Chemical

Mesh：

Substances：

Year: 1992 PMID： 1444316 PMCID： PMC245501 DOI： 10.1128/AAC.36.10.2342

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

21 in total

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Journal: J Infect Dis Date: 1986-06 Impact factor: 5.226

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Journal: J Antimicrob Chemother Date: 1990-11 Impact factor: 5.790

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Authors: E Rhinehart; N E Smith; C Wennersten; E Gorss; J Freeman; G M Eliopoulos; R C Moellering; D A Goldmann
Journal: N Engl J Med Date: 1990-12-27 Impact factor: 91.245

4. Method of reliable determination of minimal lethal antibiotic concentrations.

Authors: R D Pearson; R T Steigbigel; H T Davis; S W Chapman
Journal: Antimicrob Agents Chemother Date: 1980-11 Impact factor: 5.191

5. Inhibition of peptidoglycan biosynthesis by ramoplanin.

Authors: E A Somner; P E Reynolds
Journal: Antimicrob Agents Chemother Date: 1990-03 Impact factor: 5.191

6. High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections.

Authors: L M Bush; J Calmon; C L Cherney; M Wendeler; P Pitsakis; J Poupard; M E Levison; C C Johnson
Journal: Ann Intern Med Date: 1989-04-01 Impact factor: 25.391

7. Enterococci. Biologic and epidemiologic characteristics and in vitro susceptibility.

Authors: D Kaye
Journal: Arch Intern Med Date: 1982-10-25

8. Inducible, transferable resistance to vancomycin in Enterococcus faecalis A256.

Authors: D M Shlaes; A Bouvet; C Devine; J H Shlaes; S al-Obeid; R Williamson
Journal: Antimicrob Agents Chemother Date: 1989-02 Impact factor: 5.191

9. In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile.

Authors: F Biavasco; E Manso; P E Varaldo
Journal: Antimicrob Agents Chemother Date: 1991-01 Impact factor: 5.191

10. Recovery of resistant enterococci during vancomycin prophylaxis.

Authors: A H Kaplan; P H Gilligan; R R Facklam
Journal: J Clin Microbiol Date: 1988-06 Impact factor: 5.948

16 in total

Review 1. Vancomycin-resistant enterococci.

Authors: Y Cetinkaya; P Falk; C G Mayhall
Journal: Clin Microbiol Rev Date: 2000-10 Impact factor: 26.132

Review 2. Current perspectives on glycopeptide resistance.

Authors: N Woodford; A P Johnson; D Morrison; D C Speller
Journal: Clin Microbiol Rev Date: 1995-10 Impact factor: 26.132

3. Pharmacological properties of NAI-603, a well-tolerated semisynthetic derivative of ramoplanin.

Authors: Daniela Jabes; Cristina Brunati; GianPaolo Candiani; Simona Riva; Gabriella Romanó; Sonia Maffioli; Rosaria Rossi; Matteo Simone; Eleonora Gaspari; Stefano Donadio
Journal: Antimicrob Agents Chemother Date: 2014-01-13 Impact factor: 5.191

4. Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation.

Authors: Predrag Cudic; James K Kranz; Douglas C Behenna; Ryan G Kruger; Hellina Tadesse; A Joshua Wand; Yuri I Veklich; John W Weisel; Dewey G McCafferty
Journal: Proc Natl Acad Sci U S A Date: 2002-05-28 Impact factor: 11.205

5. Antimicrobial susceptibilities of enterococci isolated from hospitalized patients.

Authors: M Venditti; A Tarasi; V Gelfusa; E Nicastri; A Penni; P Martino
Journal: Antimicrob Agents Chemother Date: 1993-05 Impact factor: 5.191

6. Generation of ramoplanin-resistant Staphylococcus aureus.

Authors: John W Schmidt; Adrienne Greenough; Michelle Burns; Andrea E Luteran; Dewey G McCafferty
Journal: FEMS Microbiol Lett Date: 2010-07-02 Impact factor: 2.742

Review 7. Cyclic lipodepsipeptides: a new class of antibacterial agents in the battle against resistant bacteria.

Authors: Nina Bionda; Jean-Philippe Pitteloud; Predrag Cudic
Journal: Future Med Chem Date: 2013-07 Impact factor: 3.808

8. In vitro activities of ramoplanin, selected glycopeptides, fluoroquinolones, and other antibiotics against clinical bloodstream isolates of gram-positive cocci.

Authors: T Lawrence; C Rotstein; T R Beam; E A Gorzynski; D Amsterdam
Journal: Antimicrob Agents Chemother Date: 1993-04 Impact factor: 5.191

9. Bactericidal activities of peptide antibiotics against multidrug-resistant Enterococcus faecium.

Authors: N Mobarakai; J M Quale; D Landman
Journal: Antimicrob Agents Chemother Date: 1994-02 Impact factor: 5.191

10. In vitro activity of ramoplanin against vancomycin-resistant gram-positive organisms.

Authors: L A Collins; G M Eliopoulos; C B Wennersten; M J Ferraro; R C Moellering
Journal: Antimicrob Agents Chemother Date: 1993-06 Impact factor: 5.191