Literature DB >> 1444238

Pharmacology, bio-analysis and pharmacokinetics of the vinca alkaloids and semi-synthetic derivatives (review).

O van Tellingen1, J H Sips, J H Beijnen, A Bult, W J Nooijen.   

Abstract

Vinca alkaloids have been used as chemotherapeutic agents now for over three decades. Especially during recent years, the development of a considerable number of semi-synthetic derivatives, showing attractive properties in preclinical or clinical investigations, has been reported. In this paper we shall give a critical review of the investigations presented on this matter.

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Year:  1992        PMID： 1444238

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  12 in total

Review 1.  The oral route for the administration of cytotoxic drugs: strategies to increase the efficiency and consistency of drug delivery.

Authors:  H A Bardelmeijer; O van Tellingen; J H Schellens; J H Beijnen
Journal:  Invest New Drugs       Date:  2000-08       Impact factor: 3.850

Review 2.  Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus.

Authors:  Xiaoxuan Zhu; Xinyi Zeng; Chao Sun; Shilin Chen
Journal:  Front Med       Date:  2014-08-26       Impact factor: 4.592

3.  CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.

Authors:  Vincent Courdavault; Martine Thiersault; Martine Courtois; Pascal Gantet; Audrey Oudin; Pierre Doireau; Benoit St-Pierre; Nathalie Giglioli-Guivarc'h
Journal:  Plant Mol Biol       Date:  2005-04       Impact factor: 4.076

Review 4.  Bioanalysis and pharmacokinetics of (investigational) vinca alkaloids.

Authors:  O van Tellingen
Journal:  Pharm World Sci       Date:  1994-06-10

5.  Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents.

Authors:  Seneha Santoshi; Naresh Kumar Manchukonda; Charu Suri; Manya Sharma; Balasubramanian Sridhar; Silja Joseph; Manu Lopus; Srinivas Kantevari; Iswar Baitharu; Pradeep Kumar Naik
Journal:  J Comput Aided Mol Des       Date:  2014-12-07       Impact factor: 3.686

6.  Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.

Authors:  O van Tellingen; A L Sonneveldt; J H Beijnen; W J Nooijen; J J Kettenes-van den Bosch; C Versluis; A Bult
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

7.  Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.

Authors:  O van Tellingen; J H Beijnen; W J Nooijen; A Bult
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

8.  Phase I trial of vinorelbine and diphenylhydantoin in patients with refractory carcinoma.

Authors:  Thomas E Hutson; Ram Ganapathi; Paul Elson; Tarek Mekhail; Thomas Olencki; G Thomas Budd; Ronald M Bukowski
Journal:  Invest New Drugs       Date:  2004-08       Impact factor: 3.850

9.  Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinorelbine in mice as determined by high performance liquid chromatography.

Authors:  O van Tellingen; A V Kuijpers; J H Beijnen; W J Nooijen; A Bult
Journal:  Invest New Drugs       Date:  1993 May-Aug       Impact factor: 3.850

Review 10.  Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine.

Authors:  Jeffrey A Silverman; Steven R Deitcher
Journal:  Cancer Chemother Pharmacol       Date:  2012-12-05       Impact factor: 3.333
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