Literature DB >> 14434518

Effect of 5-hydroxytryptamine and iproniazid on pregnancy.

E POULSON, M BOTROS, J M ROBSON.   

Abstract

The effects of 5-hydroxytryptamine and iproniazid on pregnancy in mice and rabbits were investigated. 5-Hydroxytryptamine can interrupt pregnancy at all stages in mice but is particularly effective early and late in pregnancy. Iproniazid exerts its action essentially in the first half of pregnancy. 5-Hydroxytryptamine produces striking hemorrhage in the placenta.

Entities:  

Keywords:  IPRONIAZID/pharmacology; PREGNANCY/physiology; SEROTONIN/pharmacology

Mesh：

Substances：

Year:  1960        PMID： 14434518     DOI： 10.1126/science.131.3407.1101

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  The action of drugs on the embryo. Pharmacological considerations.

Authors:  J M ROBSON
Journal:  Proc R Soc Med       Date:  1963-07

2.  Effect of iproniazid on pregnancy.

Authors:  E FLUCKIGER; R SALZMANN
Journal:  Experientia       Date:  1961-03-15

3.  Antagonists of the embryocidal effect of 5-hydroxytryptamine in the rat.

Authors:  P J Fraser
Journal:  Br J Pharmacol       Date:  1970-05       Impact factor: 8.739

4.  Embryotoxic and teratogenic action of 5-hydroxytryptamine: mechanism of action in the rat.

Authors:  P B Marley; J M Robson; F M Sullivan
Journal:  Br J Pharmacol Chemother       Date:  1967-11

5.  5-Hydroxytryptamine, placental function and toxaemia of pregnancy.

Authors:  J M Robson; F M Sullivan
Journal:  Proc R Soc Med       Date:  1966-08

6.  Analysis of actions of 5-hydroxytryptamine in pregnancy.

Authors:  J M Robson; F M Sullivan
Journal:  J Physiol       Date:  1966-06       Impact factor: 5.182

Review 7.  The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation.

Authors:  Tina Napso; Hannah E J Yong; Jorge Lopez-Tello; Amanda N Sferruzzi-Perri
Journal:  Front Physiol       Date:  2018-08-17       Impact factor: 4.566

Review 8.  Dopamine in the Pathophysiology of Preeclampsia and Gestational Hypertension: Monoamine Oxidase (MAO) and Catechol-O-methyl Transferase (COMT) as Possible Mechanisms.

Authors:  Wendy N Phoswa
Journal:  Oxid Med Cell Longev       Date:  2019-11-28       Impact factor: 6.543

9.  Serotonin in the developing mammal.

Authors:  G PEPEU; N J GIARMAN
Journal:  J Gen Physiol       Date:  1962-01       Impact factor: 4.086
  9 in total

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