Literature DB >> 14430449

Syphilitic paroxysmal cold haemoglobinuria. Case report and study of the Coombs test.

D J PARISH, J R MITCHELL.   

Abstract

A case of congenital syphilis which presented with paroxysmal cold haemoglobinuria is described. The patient had aortic incompetence, and the significance of this finding is discussed. The Coombs test was studied, and positive results appear to be due to interaction between antiglobulin serum and complement adsorbed on to the test cells, this adsorption being promoted by the cold antibodies.

Entities:  

Keywords:  HEMOGLOBINURIA, PAROXYSMAL/case reports; SYPHILIS, CONGENITAL/case reports

Mesh:

Year:  1960        PMID: 14430449      PMCID: PMC480058          DOI: 10.1136/jcp.13.3.237

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  2 in total

1.  Cardioaortic involvement in congenital syphilis with co-existent rheumatic heart disease.

Authors:  F J T BOWIE; R G SIMPSON
Journal:  Br Heart J       Date:  1953-04

2.  The mechanism of hemolysis in paroxysmal cold hemoglobinuria. II. Observations on the behavior and nature of the antibody.

Authors:  W S JORDAN; L PILLEMER; J H DINGLE
Journal:  J Clin Invest       Date:  1951-01       Impact factor: 14.808

  2 in total
  1 in total

1.  Complement and cold agglutinins. I. Complement coating of normal human erythrocytes by cold agglutinins.

Authors:  J T Boyer; C F Hinz
Journal:  Clin Exp Immunol       Date:  1967-03       Impact factor: 4.330

  1 in total

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