Literature DB >> 1443043

Synaptophysin expression in "ependymal tumors" induced by ethyl-nitrosourea in rats.

J Vaquero1, S Coca, M Zurita, S Oya, A Arias, M Moreno, C Morales.   

Abstract

Synaptophysin expression was studied in seven "ependymomas" induced by transplacental administration of ethyl-nitrosourea in rats. In all the cases, strong positivity for synaptophysin was found on tumor cells. This finding supports previous studies suggesting that ENU-induced brain tumors considered to be ependymal neoplasms, are, in fact, primitive neuroectodermal tumors.

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Year:  1992        PMID: 1443043      PMCID: PMC1886665     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


  10 in total

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Authors:  P Kleihues; P L Lantos; P N Magee
Journal:  Int Rev Exp Pathol       Date:  1976

2.  Experimental brain tumours induced in rats by nitrosourea derivatives. II. Morphological aspects of nitrosoethylurea tumours obtained by transplacental induction.

Authors:  E Grossi-Paoletti; P Paoletti; D Schiffer; A Fabiani
Journal:  J Neurol Sci       Date:  1970-12       Impact factor: 3.181

3.  Tumours of the nervous system induced in rats by the neonatal administration of N-ethyl-N-nitrosourea.

Authors:  E L Jones; C E Searle; W T Smith
Journal:  J Pathol       Date:  1973-02       Impact factor: 7.996

4.  Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics.

Authors:  E Grossi-Paoletti; P Paoletti; S Pezzotta; D Schiffer; A Fabiani
Journal:  J Neurosurg       Date:  1972-11       Impact factor: 5.115

5.  Ultrastructure of human and experimental ependymomas. A comparative study.

Authors:  H H Goebel; H Cravioto
Journal:  J Neuropathol Exp Neurol       Date:  1972-01       Impact factor: 3.685

6.  Ultrastructural findings in so-called ependymal rat tumors induced by transplacental administration of ethylnitrosourea (ENU).

Authors:  T I Mandybur; M M Alvira
Journal:  Acta Neuropathol       Date:  1982       Impact factor: 17.088

7.  Experimental ependymomas: in vivo and in vitro morphology.

Authors:  H D Mennel; J Bücheler
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1974

8.  Synaptophysin: a reliable marker for medulloblastomas.

Authors:  K Schwechheimer; B Wiedenmann; W W Franke
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987

9.  Expression of pan-neuroendocrine proteins in 53 neuroblastic tumors. An immunohistochemical study with neuron-specific enolase, chromogranin, and synaptophysin.

Authors:  Y Hachitanda; M Tsuneyoshi; M Enjoji
Journal:  Arch Pathol Lab Med       Date:  1989-04       Impact factor: 5.534

10.  Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations.

Authors:  D Schiffer; M T Giordana; S Pezzotta; C Lechner; P Paoletti
Journal:  Acta Neuropathol       Date:  1978-01-19       Impact factor: 17.088

  10 in total
  7 in total

1.  Lectin histochemistry of ethylnitrosourea-induced oligodendrogliomas in the rat.

Authors:  J Figols; H Kroh; F F Cruz-Sánchez; J Cervós-Navarro
Journal:  J Neurooncol       Date:  1997-02       Impact factor: 4.130

2.  Glioma morphology and tumor-induced vascular alterations revealed in seven rodent glioma models by in vivo magnetic resonance imaging and angiography.

Authors:  Sabrina Doblas; Ting He; Debbie Saunders; Jamie Pearson; Jessica Hoyle; Nataliya Smith; Megan Lerner; Rheal A Towner
Journal:  J Magn Reson Imaging       Date:  2010-08       Impact factor: 4.813

3.  Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas.

Authors:  P E Kish; M Blaivas; M Strawderman; K M Muraszko; D A Ross; B D Ross; G McMahon
Journal:  J Neurooncol       Date:  2001-07       Impact factor: 4.130

4.  Neuronal lineage in ethyl-nitrosourea-induced brain tumors.

Authors:  M Shibutani
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

5.  Neuroblastic differentiation in ethyl-nitrosourea-induced brain tumors.

Authors:  J Vaquero; S Coca; M Zurita; S Oya
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

6.  Experimental induction of primitive neuro-ectodermal tumours in rats: a re-appraisement of the ENU-model of neurocarcinogenesis.

Authors:  J Vaquero; S Oya; S Coca; M Zurita
Journal:  Acta Neurochir (Wien)       Date:  1994       Impact factor: 2.216

7.  Evidence for an origin of ethyl-nitrosourea-induced rat central nervous system tumors from pluripotent germinal neuroepithelium.

Authors:  M Shibutani; K Mitsumori; R Okeda; T Imazawa; A Maekawa; H Hatanaka; M Takahashi; K Inoue; Y Hayashi
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

  7 in total

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