Literature DB >> 144232

Dedifferentiation of lens epithelial cells in tissue culture.

A J Vermorken, A A Groeneveld, J M Hilderink, R DeWaal, H Bloemendal.   

Abstract

Lens epithelial cells can be kept in their original differentiated state or brought to dedifferentiation depending on the culture conditions. The different stages of differentiation can be identified using specific markers, namely the activity of steroid metabolizing enzymes, and the synthesis of specific structural lens polypeptides. For this reason lens epithelial cells in tissue culture provide a unique system for the study of the regulation of RNA and protein biosynthesis.

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Year:  1977        PMID： 144232     DOI： 10.1007/bf00420396

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  9 in total

1.  Hydroxylation of dehydroepiandrosterone in the eye lens.

Authors:  A J Vermorken; R de Waal; W J van de Ven; H Bloemendal; P T Henderson
Journal:  Biochim Biophys Acta       Date:  1977-02-28

2.  Metabolism of dehydroepiandrosterone in the eye lens epithelium.

Authors:  A J Vermorken; W J van de Ven; W H Gielen; H Bloemendal; H C Ketelaars
Journal:  Exp Eye Res       Date:  1977-03       Impact factor: 3.467

3.  [DNA and protein synthesis in cultured lens epithelial cells. II. Activity of synthetic effectors].

Authors:  M Iwig; D Glässer
Journal:  Acta Biol Med Ger       Date:  1975

4.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

5.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

6.  Hemoglobin messenger ribonucleic acid. Distribution of the 9S ribonucleic acid in polysomes of different sizes.

Authors:  M J Evans; J B Lingrel
Journal:  Biochemistry       Date:  1969-03       Impact factor: 3.162

7.  The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  K Weber; M Osborn
Journal:  J Biol Chem       Date:  1969-08-25       Impact factor: 5.157

8.  Polyribosomes from calf-lens epithelium.

Authors:  H Bloemendal; J Schoenmakers; A Zweers; R Matze; E L Benedetti
Journal:  Biochim Biophys Acta       Date:  1966-07-20

9.  [DNA and protein synthesis in cultured lens epithelial cells. I. Test system].

Authors:  M Iwig; D Glässer
Journal:  Acta Biol Med Ger       Date:  1975
  9 in total
  1 in total

1.  Growth and differentiation of human keratinocytes cultured on eye lens capsules.

Authors:  M C Lenoir; B A Bernard; J Ferracin; B Shroot; A J Vermorken
Journal:  Arch Dermatol Res       Date:  1985       Impact factor: 3.017
  1 in total

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